Not all of the listed courses are given each year. The course is offered in the language in which it is described.
Course codes in parentheses are for Carleton University. A 3-unit course at the University of Ottawa is equivalent to a 0.5-unit course at Carleton University.
TOX8156 PRINCIPLES OF TOXICOLOGY (3 units)
The basic theorems of toxicology with examples of current research problems. The concepts of exposure, hazard and risk assessment will be defined and illustrated with experimental material from some of the more dynamic areas of modern research.
TOX8157 CHEMICAL TOXICOLOGY (3 units)
Advanced course in chemical toxicology dealing with both chemical hazards and exposure. Overview of empirical data relating to the toxicity of various classes of chemicals for test organisms, followed by study of toxicity at the cellular level, including studies of interactions between toxic substances and enzymatic systems. Data applicable to the interpretation and monitoring of WHMIS health regulations. Initial events in enzyme induction and mutagenesis. Study of predictive capabilities in the areas of structure-activity relationships and mechanisms of enzyme induction, followed by assessment of mechanisms of exposure to toxic chemicals.
TOX9104 ECOTOXICOLOGY (3 units)
Selected topics and advances in ecotoxicology with emphasis on the biological effects of contaminants. The potential for biotic perturbance resulting from chronic and acute exposure of ecosystems to selected toxicants will be covered along with the methods pesticide, herbicide and pollutant residue analysis and the concept of bound residues.
TOX9105 SEMINAR IN TOXICOLOGY (3 units)
A one-session course in seminar format highlighting current topics in toxicology. The student will present a seminar and submit a report on the seminar topic. Student, faculty and invited seminar speakers.
TOX9106 (BIOL 6406) GENETIC TOXICOLOGY (3 units)
Topics in mutagenesis and DNA repair, including spontaneous and induced mutagenesis, genetic toxicology testing, the genetics and biochemistry of replication, DNA repair and recombination, and the role of mutagens in the development of genetic disease and cancer.
BIO5103 (BIOL 5003) ADVANCED BIOCHEMISTRY (3 units)
Advanced topics in biochemistry: the chemical structure and function of biological macromolecules, biochemical thermodynamics, metabolism, photosynthesis, lipids and membranes.
BIO5305 (BIOL 5407) BIOSTATISTICS I (3 units)
Application of statistical analyses to biological data. Topics include ANOVA, regression, GLMs, and may include loglinear models, logistic regression, general additive models, mixed models, bootstrap and permutation tests. Prerequisites: Graduate standing, courses in elementary ecology and statistics and permission of the department.
BIO5306 (BIOL 5409) MODELLING FOR BIOLOGISTS (3 units)
Use and limitations of mathematical and simulation modelling approaches for the study of biological phenomena.
BIO8109 (BIOL 6001) ADVANCED MOLECULAR BIOLOGY (3 units)
In-depth coverage of the structure, function, and synthesis of DNA, RNA, and proteins.
BIO8116 (BIOL 6002) ADVANCES IN PLANT MOLECULAR BIOLOGY (3 units)
Use of molecular genetics in general plant biology and the contribution of plant genomics to our understanding of plant metabolism, plant development, and plant interactions with the environment at the molecular, genome, and cellular levels. Prerequisite: BIO8109/61.601F1 and this course normally will be offered together in the same year but only in alternate years.
BIO8162 (BIOL 5402) ADVANCED ENDOCRINOLOGY (3 units)
Major topics in comparative endocrinology: understanding the structure, function and evolution of vertebrate endocrine systems, including endocrine disruption. Prerequisite: An undergraduate Endocrinology course (BIO4127 or equivalent).
BIO8306 (BIOL 5508) ADVANCED TOPICS IN ECOLOGY (3 units)
Recent developments in population, community and/or ecosystem ecology.
BIO8307 (BIOL 5509) ADVANCED TOPICS IN ECOLOGY II (3 units)
Lectures, seminars and discussions on current literature on experimental approaches, concepts and findings in population and community ecology, ecosystem and landscape ecology and biostatistics. Course content to complement that of BIO 8306/BIOL 5508; not necessary to take the two in a particular order.
BIO8365 (BIOL 5802) ADVANCED BEHAVIOURAL ECOLOGY (3 units)
Recent advances in behavioural ecology including topics such as the evolution of tactics and strategies of group living, foraging, anti-predation, resource use and defence, cooperation, reproduction, and parental care.
CHM8126 (CHEM 5303) BIOORGANIC CHEMISTRY (3 units)
Overview of recent developments in the mechanistic understanding of selected enzyme-catalyzed reactions. Topics include Cytochrome P450, methane monooxygenase, biotin and lipoic acid biosynthesis, methyl transfer, Vitamin B12, lipoxygenase, prostaglandin synthase; etc. Emphasis will be placed on biotransformations which are relatively poorly understood from a mechanistic point of view.
CHM8322 (CHEM 5203) TOPICS IN COORDINATION CHEMISTRY (1.5 units)
Brief introduction to basic concepts in coordination chemistry. Topics to include the following: carbon dioxide fixation, dinitrogen fixation, activation, olefin metathesis, nature of the M-M bond.
CHM8327 (CHEM 5005) PHYSICAL ORGANIC CHEMISTRY (1.5 units)
Hammet functions, transition state energies, stereochemistry of organic compounds, and mechanisms of organic reactions and their determination.
CHM8329 (CHEM 5402) MEDICINAL CHEMISTRY (1.5 units)
Preparation of drugs, their mode of action, their use in treating of disease. Evolution of medicine due to chemistry. Discussion of metabolic pathways and their modification to control and/or circumvent disease.
CHM8331 (CHEM 5300) PHYSICAL CHEMISTRY OF BIOLOGICAL MACROMOLECULES (1.5 units)
Focus on how the application of physical techniques normally applied to small molecules, can be used to study macromolecular structure and function of DNA and proteins. Examples of applications to include: kinetics, electrochemistry, equilibria phemonmena (thermodynamics).
CHM8332 (CHEM 5301) ELECTROCHEMICAL PHENOMENA IN BIOLOGICAL SYSTEMS (1.5 units)
Description of theory accounting for the generation of membrane potentials. Application to the generation of nerve impulses.
CHM8333 (CHEM 5302) SURFACE PHENOMENA IN BIOLOGICAL SYSTEMS (1.5 units)
Description of theory of surface tension phenomena in aqueous systems. Discussion of effects of cell and macromolecular structures in biological systems.
CHM8348 (CHEM 5500) ANALYTICAL INSTRUMENTATION (1.5 units)
Principles of modern electronics, devices and instruments. Measurement of photonic and electrochemical signals. Conditioning of signals for feedback control and microcomputer interfacing. Computational data analysis techniques such as simplex optimization. Applications in chemical analysis include amperometric detector for capillary electrophoresis, and surface plasmon resonance immunosensor.
CHM8349 (CHEM 5304) FREE RADICALS IN CHEMISTRY AND BIOLOGY (1.5 units)
Oxidative stress induced by free radicals plays a significant role in most fatal and chronic diseases. The chemistry of bio-radicals will be described and related to pathobiological processes such as lipid peroxdiation and atherosclerosis, protein nitration and cross linking, and DNA scission.
CHM8352 (CHEM 5501) ANALYTICAL APPROACH TO CHEMICAL PROBLEMS (1.5 units)
Case study of analytical approach to various chemical problems in agricultural, biochemical, environmental, food processing, industrial, pharmaceutical and material sciences. Analytical methods include capillary electrophoresis, chemiluminescence, Fourier transform infrared spectroscopy, inductively coupled plasma emission spectroscopy, mass spectrometry, biochemical sensors, and fiber optics for remote sensing.
CHM8353 (CHEM 5502) TRACE AND ULTRATRACE ANALYTICAL CHEMISTRY (3 units)
Criteria for evaluation and selection of analytical techniques and methods. Electroanalytical techniques. Simultaneous and sequential multielement determination. Atomic absorption, atomic emission and atomic fluorescence spectrometry, using optical spectrometric and mass- spectrometric determination. Applications of these techniques at trace and ultratrace levels in complex matrices.
CHM8354 (CHEM 5503) CHEMICAL SPECIATION IN THE NATURAL ENVIRONMENT (3 units)
Evaluation of analytical techniques and their capability for quantitative determination of chemical species (as opposed to total element-determination) in the natural environment. Electro- chemical techniques for determination of chemical speciation of nutrient and toxicant elements present in the natural environment.
GEO5136 (ERTH 5306) PALEOBIOLOGY (3 units)
Selected topics in paleobiology of micro- and macro-invertebrates and vertebrates. Topics include extinctions, micro- and macro-evolutionary processes, long-term trends and cycles in the Phanerozoic, and functional morphology, as well as application of invertebrates to biostratigraphy, paleoceanography and paleolimnology.
GEO5141 (GEOL 5401) PERMAFROST HYDROLOGY AND INVESTIGATIVE METHODS
An examination of groundwater flow in permafrost regions. The importance of groundwater in the formation of various types of ground ice, and the effect of groundwater flow on permafrost distribution.
GEO5142 (GEOL 5402) ENVIRONMENTAL GEOSCIENCE (3 units)
A study-seminar course in which students will examine, in depth, certain environmental problems, including geological hazards, mineral and energy consumption and environmental degradation. The relation between development and the environment will be considered. Students will prepare a report and present a seminar on a subject of their choice, and will participate in a research project centered in the Ottawa area.
GEO5143 (GEOL 5403) ENVIRONMENTAL ISOTOPES AND GROUNDWATER GEOCHEMISTRY (3 units)
Stable environmental isotopes (18O, 2H, 13C, 34S, 15N) in studies of groundwater origin and flow, and geothermal studies. Groundwater dating techniques involving tritium and radiocarbon, and exotic radioisotopes (e.g. 36Cl, 39Ar, 85Kr). Low temperature aqueous geochemistry and mineral solubility with emphasis on the carbonate system. Some applications to paleoclimatology will be discussed. Prerequisite: Fourth-year Hydrogeology (67.420 or GEO 4342) or equivalent.
GEO5147 (ERTH 5407) GEOCHEMISTRY OF NATURAL WATERS (3 units)
Aqueous speciation, solubility of metals, minerals and gas, reaction kinetics and equilibria. Chemistry and dynamics of groundwaters and hydrothermal fluids.
GEO5153 (ERTH 5503) COMPUTER TECHNIQUES IN THE EARTH SCIENCES (3 units)
A practical course in the application of computer techniques in the acquisition and interpretation of geoscientific data. Topics will be selected from the following: remote sensing and geographic information systems; geostatistical analysis techniques; analysis and modelling of geoscientific data. Prerequisite: Permission of the Institute.
GEO5163 (ERTH 5603) STABLE ISOTOPE GEOCHEMISTRY (3 units)
Mechanisms of isotope fractionation, fractionation in nature; physical and chemical isotope fractionation, kinetic isotope effects. Variations of stable isotope ratios (hydrogen, carbon, oxygen and sulphur) in nature. Preparation techniques of natural samples for isotope analysis. Applications of stable isotopes to study magma genesis, ore genesis, nature of water and formation fluids and sedimentary environments.