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RESEARCH
Office of the
Vice-Rector, Research

 
 
 
 
 
 
 
 
 
 
 
 
   


Research perspectives


 

SPRING/SUMMER 2001 — Volume 4, No. 2

Inside

Centre Stage | Small is not just Beautiful, but also Practical
Rescuing Ordinary Folk from Obscurity | Looking into the Light
Linda Cardinal Explores the Politics of Language | Imprint | Contacts

 

Two of our Professors are among Canada’s
Top 40 Under 40!

By Christel Binnie

The Report on Business magazine recently published its seventh annual Top 40 Under 40 profiling the ‘best and brightest’ young Canadians on the rise. Among these forty individuals are Steffany Bennett and May Griffith, two University of Ottawa research scientists breaking new ground in stem cell research and tissue engineering.

Steffany Bennett

  Steffany Bennett is making
  important progress in the fight
  against Alzheimer Disease.


  Photo by: David Barbour


May Griffith

  May Griffith has engineered the
  first functional tissue equivalent
  to a human cornea.

  Photo by: David Barbour

THE REPORT ON BUSINESS MAGAZINE recently published its seventh annual Top 40 Under 40 report profiling the ‘best and brightest’ young Canadians on the rise (May 2001). Out of these 40 amazing individuals, seven are research scientists, and two of these, Steffany Bennett and May Griffith, are at the University of Ottawa.

The annual competition, conducted by Toronto-based executive search firm Caldwell Partners International, received over 700 nominations. Nominees were evaluated by a panel of business and community leaders using several criteria, including: vision, innovation, community involvement, and strategy for growth.

STEFFANY BENNETT joined the University of Ottawa in 1999 as an assistant professor in the Department of Biochemistry, Microbiology and Immunology. That same year, Bennett was named a Lefler Scholar at Harvard Medical School. Her research collaboration with David Paul at Harvard (Neurobiology) takes her to Boston every 6 to 8 weeks to perform experiments. Bennett and Paul are developing a mouse model of neural stem cell enrichment — stem cells represent the latest great scientific discovery, and have the potential to cure an array of degenerative diseases.

Fascinated by how the brain works and sensitive to individuals facing the tragedy of losing cognitive function, Bennett’s research group is striving to reduce the rate of cell death in patients with Alzheimer Disease and other degenerative cognitive disorders by using experimental models. “Patients suffering from Alzheimer increasingly retreat into their own world of memory loss, frustration and loneliness,” says Bennett. “In the later stages of the disease, they are unable to sustain an independent existence and are dependent upon family and, ultimately, health care institutions for basic care...we have to do something!”

Bennett feels honoured to be recognized as one of Canada’s Top 40 Under 40. “It’s humbling to be recognized, but I have to say that it’s not all about me,” she says. She is grateful for the support from her colleagues in the Department of Biochemistry, Microbiology, and Immunology as well as the administrative support from the Faculty. “I have been given two years of teaching relief and the supportive, intellectually stimulating environment of this department has enabled me to rapidly establish a productive research program,” explains Bennett.

Research in Bennett’s lab focuses on two complementary programs. The first program is designed to reduce progressive neural loss, which is the main research focus and includes collaborations with Bruce Pappas at Carleton University’s Institute of Neuroscience and Mary-Ellen Harper at the University of Ottawa’s Department of Biochemistry, Microbiology, and Immunology. The second program is designed to regenerate damaged cerebral tissue, which is done in collaboration with David Paul at Harvard Medical School.

Bennett has received a Premier’s Research Award of Excellence to recruit up-and-coming young scientists into her lab. This recruitment has generated something reminiscent of an “all-women-band,” with a total of eight female research assistants. The chemistry between these researchers is impressive and Bennett is seen as the “North Star... the one that shines the most and is there to guide us,” says Fanny Morin, an MSc candidate. Lysanne Melanson-Drapeau, an NSERC summer student, describes Bennett as “being full of energy and optimism,” Sophie Imbeault, another NSERC summer student says, “it is inspiring to see someone as young as Stef in charge of her own lab, and it drives me to work hard in the hopes that I can achieve my goals and be successful like her.” Sandy Bekyo, who is submitting her MSc thesis this summer, found her first lab experience to be great and enjoys the company of her “intelligent and hard-working” colleagues.

Bennett’s accomplishments reflect her drive, passion and commitment to excellence in research, but her passion doesn’t stop there. She is the drummer in a band called Black Boot Trio. The band reaches down into the roots of country, with a contemporary twist and they have often been compared to early Johnny Cash. The band began in 1990 and has played in small and medium sized venues in Ottawa, Toronto, Halifax, Montréal, Fredericton and Moncton, among other locations. Steffany Bennett certainly rocks!

MAY GRIFFITH arrived at the University of Ottawa in 1993 and is an associate professor at the Departments of Cellular and Molecular Medicine, and Ophthalmology. She is also a scientist at the Ottawa Health Research Institute (OHRI). Griffith is a cell biologist whose expertise is in tissue engineering. She developed the first functional tissue equivalent to a human cornea, which is currently undergoing industry laboratory testing as a possible alternative to using animals for product testing. A large part of Griffith’s success results from her ability to establish and coordinate scientific collaborations with other scientists, creating a network of specialists in diverse backgrounds working together to solve challenging problems. Not only has Griffith established strong university-industry based partnerships with companies in the US and Japan, she has also received a Premier’s Research Excellence Award, an NSERC Women’s Faculty Award as well as the University of Ottawa’s Young Researcher Award.

Griffith’s interdisciplinary approach to research extends to the type of students that work with her. “The people in my lab come from different academic backgrounds; they learn to get along and learn from each other,” says Griffith. “This environment allows them to get trained in an interdisciplinary area, which I think will be good for their future.” Griffith also admits, “I generally share students, supplies, even across country borders, with my colleagues...it’s just a lot more fun for everyone.”

One of her on-going collaborations is with Shigeto Shimmura at the Department of Ophthalmology at the Tokyo Dental College in Japan. Shimmura is an experimental surgeon who has pioneered several cornea techniques. Further to developing a transplantable artificial cornea, Shimmura is also helping surgeons at the University of Ottawa Eye Institute with new surgical techniques. Griffith is also collaborating with Masatsugu Nakamura at the Santen Pharmaceutical Company, Nara, Japan. This collaboration is geared at developing an innervated cornea for drug testing. Travelling to Japan has its perks, admits Griffith. “I get to eat lots of sushi, which I really love. I have also learned to travel with long lasting batteries for my laptop.”

Although Griffith has received several awards over the years, she feels that being a Top 40 Under 40 is a great honour. “What it really means is that I am blessed with — and maybe also smart enough to find — many great collaborators, friends and students who have helped me along the way. So, I think the award really goes to them.”

Griffith also believes that her research and having fun go hand-in-hand. “I always enjoyed sculpting, building things, and in general, playing. So playing with matrix molecules (natural polymers) and cells, and seeing what they do, which is the foundation of tissue engineering, came fairly naturally... I enjoy working here, and I will keep doing research as long as it’s fun!”


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