Leonard Maler

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Leonard Maler
Full Professor

BSc - McGill - 1967
Ph.D. (Brain Sciences) MIT - 1973

Room: Rm. 2233 RGN
Office: 613-562-5800 ext. 8189
Work E-mail: lmaler@uottawa.ca

Leonard Maler

Biography

Feedback Regulation of Sensory Processing in a Neural Network Underlying Communication and Electrolocation.

All sensory systems of vertebrates have extensive feedback input, but its function is still obscure. Dr. Maler's research has focused on feedback input in the electrosensory system, which is especially amenable to detailed analysis at both the circuit and cellular levels. Morphological, electrophysiological, and computational techniques are used to investigate how the patterns of connectivity, the properties of neuronal ion channels and the behaviour of modifiable synapses act in concert to allow feedback input to modulate the spatio-temporal filtering of sensory systems.

A second project of this group is to examine the cellular properties of a neuronal group which controls aggressive and reproductive communication in electric fish. Immunohistochemical and electrophysiological techniques are used to study the interactions of transmitters (peptides and amino acids) and intrinsic voltage-sensitive ion channels in determining the quality of the communicatory output. A major goal of these investigations is to identify the cellular basis of the seasonal variations in aggressive/reproductive communication.

Keywords:

cerebellum neural computation, Learning, Spatial Learning, Memory, Feedback, Signal processing

Fields of Interest

  • Feedback regulation of sensory processing in a neural network underlying communication and electrolocation
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