David A. Grimes

Carte électronique

David A. Grimes
Associate Professor

Pièce : C2, Civic CMM/Neurology
Bureau : 613-798-5555 poste 18162
Courriel professionnel : dagrimes@ohri.ca

David A. Grimes


Associate Scientist, Neuroscience, Ottawa Hospital Research Institute

Associate Professor, Division of Neurology, Department of Medicine, University of Ottawa

Director, Parkinson's Disease and Movement Disorders Clinic at The Ottawa Hospital

Co-Director of the Parkinson Research Consortium, Ottawa Health Research Institute

Biographical sketch

Dr. Grimes received his Doctorate in Medicine and completed his residency in Neurology at the University of Ottawa. He spent two years at the Toronto Hospital and the Centre for Research in Neurodegenerative Diseases as a research fellow in movement disorders and molecular genetics. He joined the Department of Medicine in Ottawa in 1999. His major clinical interests are in the diagnosis and treatment of a wide variety of movement disorders with an emphasis on Parkinson's disease and dystonia. As a basic scientist, he is interested in identifying mutated genes that cause Parkinson's disease and other movement disorders. He has received grants from the Parkinson's Society Canada, the Parkinson's Society of Ottawa-Carleton, the Dystonia Medical Research Foundation and the Myoclonus Research Foundation. Other professional activities include membership in the American Academy of Neurology, the Canadian Neurological Society, the Canadian Movement Disorder Group, the Parkinson Study Group and the Movement Disorder Society. He is a reviewer for the Movement Disorders Journal, Canadian Journal of Neurological Sciences, Brain, and Canadian Medical Association Journal. He is also the medical advisor for the Parkinson Society Ottawa. He received the Queen's Golden Jubilee Medal in 2002 for his work in Parkinson's disease.


He is interested in the diagnosis and treatment of movement disorders including Parkinson's disease, dystonia, chorea, tics and myoclonus. He conducts clinical trials in Parkinson's disease and dystonia exploring novel treatment options. He has extensive experience with botulinum toxin injections for the treatment of focal dystonia and hemifacial spasm.


Exploring the role of genes that cause or contribute to the development of abnormal movements. Currently involved in trying to identify a novel gene mutation for Parkinson's disease and for inherited myoclonus dystonia.


Involved in local teaching of movement disorders to undergraduate and post-graduate students. Also involved in teaching at the national level, giving lectures at the movement disorders review course to senior neurology residents and at review courses at the annual Canadian Congress of Neurologic Science meetings.

Key Words:

genetics, Parkinson's Disease, movement disorders (dystonia, chorea, myoclonus, tremor, tics, stereotypies), Botulinum toxin

Champs d'intérêt

  • Parkinson's Disease
  • Movement disorders
  • Genetics
  • Clinical studies
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