Matthew Holahan

Carte électronique

Matthew Holahan
Professor/ PhD/ Carleton University Department of Neuroscience



I have a strong background in the design of behavioural and neurobiological experiments related to learning, memory and psychopharmacology. I completed my undergraduate degree in Psychology (1995) at the University of Wisconsin and worked in a psychopharmacology lab for two years where I contributed to a program of research uncovering the neural substrates of addiction at the behavioural, pharmacological and molecular levels. I did my MSc and PhD (2003) under Norman White at McGill University, where I studied the impact of conditioned fear on memory storage processes and the role of the amygdala.  As a post-doctoral fellow at Northwestern University with Aryeh Routtenberg (2003 – 2006), I designed behavioural and pharmacological studies to investigate transgenic mouse models of Alzheimer’s disease and molecular and systems levels contributions to memory.  I have been at Carleton University since 2006 in the Department of Neuroscience where I am a full professor.

Research Interests:

Currently, my laboratory research is focused on the developmental emergence of spatial/ cognitive function in rodents, preclinical models of psychiatric and neurodegenerative diseases (Parkinson’s disease), the effect of environmental toxins on brain development and various aspects of concussion.  We use ex vivo models, cell culture in vitro models, behavioral experiments and a variety of neural analyses (e.g. Westerns, immunos, unbiased stereology, Golgi and neuron reconstruction, PCR).

Champs d'intérêt

  • Concussion
  • Parkinson’s
  • spatial memory
  • development
  • phthalates
  • addiction
  • rodents
  • microscopy
  • Neurodegeneration
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