CIHR Project Grants support high-impact health research across the full spectrum of disciplines. These grants provide critical funding to develop new treatments, improve health systems, and advance our understanding of pressing medical challenges—from heart disease and cancer to public health policy and artificial intelligence in diagnostics.
The following faculty members and affiliated researchers were awarded funding in this latest competition:
CIHR Project Grant Recipients
Morgan Fullerton (BMI): “Metabolic regulation of anabolism suppresses atherogenesis”
Hawre Jalal (SEPH): “Predicting the Current and Future Burden of Lyme Disease with a Platform for Integrating Computation, Analysis, and Simulation for Ontario (PICASO)”
Giorgia Sulis (SEPH): “A feasibility study of a context-specific antibiotic stewardship intervention among physicians in Nigeria's private outpatient facilities”
David Cook (OHRI/CMM): “Targeting cancer cell plasticity to improve outcomes in high-grade serous ovarian cancer”
Angela Crawley (OHRI/BMI): “Identifying CD8 T Cell Immunometabolic Scars in Chronic HCV and Metabolic Liver Disease and Their Impact on HCC Responses”
Darine El-Chaar (OHRI/SEPH/OBGYN): “Assessing maternal and infant health outcomes following immunization for respiratory syncytial virus (RSV) disease”
Jess Fiedorowicz (OHRI/SEPH/Psychiatry): “Canadian Extension of the Candesartan Adjunctive Bipolar Depression Trial (CADET)”
Natasha Kekre (OHRI/SEPH/Medicine): “Canadian-Made CD19 CAR-T Therapy for Refractory Systemic Sclerosis, from the Canadian Led Immunotherapies Collaborative (CLIC-03 Trial)”
Douglas Manuel (OHRI/SEPH/Family Medicine): “Leveraging a New National Data Linkage to Examine Caregiving for Older Adults and Its Impacts on Caregivers' Downstream Outcomes”
Marie-France Savard (OHRI/Medicine): “A pragmatic, multicenter randomized study evaluating the benefits and risks of adjuvant endocrine therapy in patients aged 70 years or older with low-risk breast cancer (REaCT-70 Study).”
Jing Wang (OHRI/CMM): “Monoacylglycerol lipase (Mgll)-regulated 2-AG/eCBR signaling in feeding circuits controls adult neurogenesis”
Emilio Alarcón (UOHI/BMI): “LuzCornea: A light activated biomimetic material for on-the-spot repairing thinning corneas”
Sharon Chih (UOHI/Medicine): “Early Initiation of Antiplatelet Therapy in Heart Transplantation - AERIAL International Trial”
Thomas Lagace (UOHI/BMI): “Molecular determinants and physiological role of PCSK9-LDL association”
Michel Le May (UOHI/Medicine): “The University Of Ottawa Dapagliflozin in ST-Elevation Myocardial Infarction Randomized Trial (DAPA-STEMI) CLINICAL TRIAL (DAPA-STEMI)”
Mireille Ouimet (UOHI/BMI): “Role of HDL in Postoperative Atherosclerosis”
Katey Rayner (UOHI/BMI): “Specialized mRNA translation regulates macrophage function in atherosclerosis”
Andrea Evans (CHEORI/SEPH/Pediatrics): “CanFos: Improving the Health of Canadian Children in Foster Homes.”
Claire Kendall (BHRI/Family Medicine): “A place-based framework for equitable health service delivery”
*Miriam Nguilefem (BHRI): “A cluster randomized controlled trial of BornFyne Prenatal Management System digital platform to support reproductive maternal care delivery in Cameroon.”
*Christopher Sun (UOHI/Telfer): “Actionable Incidental Extracardiac Findings Detection via Interactive Artificial Intelligence”
Priority Announcement Recipients
Justin Presseau (OHRI/SEPH): “Building and sustaining trust in healthcare: Co-developing a compendium of equitable strategies for building, rebuilding and maintaining trust”
William Stanford (OHRI/BMI/CMM): “Cellular and molecular pathogenesis of renal tuberous sclerosis complex”
Erin Mulvihill (UOHI/BMI): “Understanding and Treating Cardiac Fibrosis in PAI-1 Deficiency: Mechanistic Insights and Therapeutic Strategies”
*Carrie Heer (BHRI): “Breaking barriers: exploration of behavioural, social, and organizational factors influencing vaccine uptake among long-term care home residents”
*Affiliated to one of the Research Institutes, but not Faculty of Medicine.