Medical researchers in a modern laboratory conducting experiments, representing uOttawa Faculty of Medicine’s world-class research advancing the future of medicine.

Advancing the Future of Medicine Through World-Class Research

At the University of Ottawa Faculty of Medicine, we advance discovery through research excellence, innovation, and collaboration.
Combining world-class expertise, cutting-edge technology, and collaboration across disciplines we're driving discoveries that fuel tomorrow’s health innovations.

Discover our research stories

A representation of a human brain sitting on a set of dumbbell weights
Research

Can the mental health benefits of exercise be bottled?

We all know the feeling: the mental clarity that comes after a good run or a heavy workout. Science backs this up, even showing that for non-severe depression, exercise can be just as effective as antidepressants or therapy.

But there is a cruel irony at play, the symptoms of depression, such as low energy and lack of motivation, are often the very things that can stop people from moving.

illustration of synthetic peptides

Innovations by University of Ottawa medical researchers lighting the way to smarter tissue and organ repair

By harnessing the power of collagen-inspired peptides and light-triggered chemistry, a University of Ottawa research team has engineered a customizable material with potential to be a gamechanger for soft tissue repair whether it’s closing a surgical incision or sealing a traumatic wound.

In a compelling study published in Advanced Functional Materials, the collaborative team demonstrates a new strategy for creating biomimetic, entirely peptide-based hydrogels that combine strength, adaptability, and biological compatibility. Unlike many existing biomaterials used as soft tissue adhesives, it doesn’t rely on any synthetic polymers which can trigger unwanted immune responses.

Illustration of interconnected brain neurons glowing with signals, symbolizing uOttawa-led research on serotonin’s hidden role in decision-making inside the brain.

uOttawa-led research team deciphering what serotonin is saying inside our brains

Behind every decision we make lies a silent signal—serotonin isn’t just tagging experiences as positive or negative.

Thanks to world-class, interdisciplinary research at the University of Ottawa Faculty of Medicine, scientists have unveiled serotonin’s “prospective code for value”—a hidden message that predicts what’s coming next. Published in Nature, this breakthrough sheds light on how our brain calculates value, with major implications across neuroscience, psychology, and mental health.

Cancer patient wearing a headscarf after chemotherapy consults with a doctor in hospital, symbolizing uOttawa Medicine research on overcoming drug-resistant cancers.

uOttawa Medicine scientists uncover cellular mechanism behind drug-resistant cancers

Deep inside cancer cells, a hidden mechanism is at work—fueling resistance to life-saving treatments like chemotherapy and radiotherapy.

Now, scientists at the University of Ottawa Faculty of Medicine have uncovered how this process unfolds at the cellular level, revealing a crucial target that could help overcome drug resistance. This discovery opens the door to more potential therapies and renewed hope for patients facing the toughest forms of cancer.

Aerial view of the University of Ottawa Faculty of Medicine's new modern building, the future Advanced Medical Research Centre (AMRC). The multi-storey facility, marked with the University’s logo, is surrounded by green spaces, roads, and a parking lot.

Advanced Medical Research Centre: A hub where research sparks tomorrow’s health solutions

At the heart of the University of Ottawa Faculty of Medicine, the Advanced Medical Research Centre (AMRC) will spark innovation through a vibrant research community, strong partnerships, and sustained funding.

From cutting-edge infrastructure, such as state-of-the-art wet labs, to collaborative research hubs, the AMRC will soon be the place where research turns into real-world health solutions, strengthening Ottawa’s position as a leader in medical innovation.

More research stories

Macrophages Colorized scanning electron micrograph of macrophages
Newsroom

Not just a messenger: Developing nano-sized delivery agents that also provide therapeutic treatment

University of Ottawa researchers show particles can not only deliver doses to complex diseases but also contribute to treatment
Molecules
Research and innovation

Healing faster: Unveiling the future of tissue & organ repair

Combining biomedical finesse and nature-inspired engineering, a uOttawa-led team of scientists have created a jelly-like material that shows great pot…
AI generated image of microplastics on a brain
Newsroom

Plastic on the mind: Countering microplastics impact on brain, general health

Microplastics are invading our bodies, with a recent influential study highlighting a spoon’s worth of these toxic particles alone can be found in the…
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