Cyntia Duval.
Cyntia Duval
Assistant Professor


Room
GNN 284

Department of Biology

Biography

Dr. Duval earned a Bachelor of Health Biochemistry from the University of Sherbrooke before pursuing graduate studies in Pharmacology at the University of Montreal’s CHU Sainte-Justine Research Centre. Her doctoral research focused on the inflammatory mechanisms involved in pregnancy complications and placental function. Following her PhD, she held various positions in research and development before undertaking a postdoctoral fellowship at the University of Toronto’s CReATe Fertility Centre. As a postdoctoral researcher and later as Director of Translational Research, she developed a research program focused on women’s reproductive health, ovarian biology and oocyte quality, as well as the impact of environmental factors on fertility.

Dr. Duval’s research aims to better understand how contemporary exposures—including cannabinoids, metabolic disturbances, and certain pharmacological treatments—influence ovarian function, oocyte competence, early embryonic development, and the endometrial environment. Her approach combines human cohorts and animal models, cutting-edge transcriptomics and single-cell genomics technologies, and innovative models that enable the study of cellular interactions within the reproductive system.

Selected publications

  • Duval C, Wyse BA, Fuchs Weizman N, Kuznyetsova I, Madjunkova S, Librach CL. Cannabis impacts female fertility as evidenced by an in vitro investigation and a case-control study. Nature Communications, September 2025; 16(1):8185. (doi: 10.1038/s41467-025-63011-2)
  • Fuch Weizman N, Wyse BA, Duval C, Librach CL. Major depressive disorder an anti-depressant treatment radically alters the human niche DNA methylome. Reproduction. September 2025; 170(3):e240467. (doi: 10.1530/REP-24-0467)
  • Duval C, Wyse BA, Tsang B, Librach CL. Ovarian extracellular vesicles in the context of polycystic ovarian syndrome and endometriosis: a review. Journal of Ovarian Research, August 2024; 17(1):160. (doi: 10.1186/s13048-024-01480-7)
  • Duval C, Brien ME, Gaudreault V, Boufaied I, Baker B, Jones RL, Girard S. Differential effect of LPS and IL-1β in term placental explants. Placenta, January 2019; 75: 9-15. (doi: 10.1016/j.placenta.2018.11.006)

Research interests

  • Reproductive biology
  • Ovarian biology
  • Reproductive toxicology
  • Confocal imaging
  • Multi-omics technologies