Dr. Lovell specializes in the design, development, and utilization of fluorophores for biological applications. Research in the Lovell laboratory focuses specifically on: (i) developing new fluorophores to study protein dynamics that are currently inaccessible with existing probes; (ii) designing new fluorescent scaffolds for single-molecule microscopy with enhanced photostability; and (iii) establishing new single-molecule fluorescence microscopy methods.
Selected publications
- Lovell, T. C.*; Branchaud, B. P.; Jasti, R.* An Organic Chemist’s Guide to Understanding Common and New and Unusual Fluorophores. Eur. J. Org. Chem. 2024, 27, e202301196.
- Gidi, Y. A.‡; Ramos-Sanchez, J.‡; Lovell, T. C.; Glembockyte, V.; Cheah, I. K.; Schnermann, M. J.; Halliwell, B.; Cosa, G. Superior Photoprotection of Cyanine Dyes with Thio-imidazole Amino Acids. J. Am. Chem. Soc. 2023, 145, 19571–19577.
- Lovell, T. C.; Bolton, S. G.; Kenison, J. P.; Shangguan, J.; Otteson, C. E.; Civitci, F.; Nan, X.; Pluth, M. D.; Jasti, R. Biocompatible, subcellular targeted nanohoop for one- and two-photon live cell imaging. ACS Nano 2021, 15, 15285–15293.
- Lovell, T. C.; Garrison, Z. R.; Jasti, R. Synthesis, Characterization and Computational Investigation of Bright Orange-emitting Benzothiadiazole [10]Cycloparaphenylene. Angew. Chem. 2020, 59, 14363-14367.