Loss of VHL-mediated pRb regulation promotes clear cell renal cell carcinoma.Akuma M, Kim M, Zhu C, Wiljer E, Gaudreau-Lapierre A, Patterson LD, Egevad L, Tanguay S, Trinkle-Mulcahy L, Stanford WL, Riazalhosseini Y, Russell RC.Cell Death Dis. 2025 Apr 16;16(1):307. doi: 10.1038/s41419-025-07623-y.PMID: 40240354 

Ultrasound and Microbubble Mediated Delivery of Virus-Sensitizing Drugs Improves In Vitro Oncolytic Virotherapy Against Breast Cancer Cells.Italiya KS, Mullins-Dansereau V, Geoffroy K, Gilchrist VH, Alain T, Bourgeois-Daigneault MC, Yu F.Ultrasound Med Biol. 2025 Apr 14:S0301-5629(25)00089-4. doi: 10.1016/j.ultrasmedbio.2025.03.010. Online ahead of print.PMID: 40234152

Therapeutic Potential of Cranberry Proanthocyanidins in Addressing the Pathophysiology of Metabolic Syndrome: A Scrutiny of Select Mechanisms of Action. Feldman F, Koudoufio M, Sané AT, Marcil V, Sauvé MF, Butcher J, Patey N, Martel C, Spahis S, Duan H, Figeys D, Desjardins Y, Stintzi A, Levy E.Antioxidants (Basel). 2025 Feb 26;14(3):268. doi: 10.3390/antiox14030268.PMID: 40227220

Estimating the Prevalence of GNE Myopathy Using Population Genetic Databases. Derksen A, Thompson R, Shaikh M, Spendiff S, Perkins TJ, Lochmüller H.Hum Mutat. 2024 Aug 29;2024:7377504. doi: 10.1155/2024/7377504. eCollection 2024.PMID: 40225917

Structure of the nucleosome-bound human BCL7A. Martin F, Kazrani AA, Lafouge J, Diaz-Jimenez DM, Siebert S, Fabbro-Burtschell L, Maillard E, Lapouge K, Mertens HDT, Sauter C, Leitner A, Ochsenbein F, Blais A, Bergamin E.Nucleic Acids Res. 2025 Apr 10;53(7):gkaf273. doi: 10.1093/nar/gkaf273.PMID: 40207634

The 16th Annual International Oncolytic Virotherapy Conference (IOVC) in Rotterdam: For the dreamers and doers of oncolytic virotherapy. Olagnier D, Alain T.Virologie (Montrouge). 2025 Apr 5;29(3):0. doi: 10.1684/vir.2025.1077. Online ahead of print.PMID: 40186367

Multiple exposures to SARS-CoV-2 Spike enhance cross-reactive antibody-dependent cellular cytotoxicity against SARS-CoV-1. Beaudoin-Bussières G, Tauzin A, Dionne K, El Ferri O, Benlarbi M, Bourassa C, Medjahed H, Bazin R, Côté M, Finzi A.Virology. 2025 Mar 22;607:110512. doi: 10.1016/j.virol.2025.110512. Online ahead of print.PMID: 4014738

Digging Through the Complexities of Immunological Approaches in Emerging Osteosarcoma Therapeutics: A Comprehensive Narrative Review with Updated Clinical Trials. Sergi CM, Burnett M, Jantuan E, Hakoum M, Beug ST, Leng R, Shen F.Biomedicines. 2025 Mar 8;13(3):664. doi: 10.3390/biomedicines13030664.PMID: 40149640 

A stress-dependent TDP-43 SUMOylation program preserves neuronal function. Suk TR, Part CE, Zhang JL, Nguyen TT, Heer MM, Caballero-Gómez A, Grybas VS, McKeever PM, Nguyen B, Ali T, Callaghan SM, Woulfe JM, Robertson J, Rousseaux MWC.Mol Neurodegener. 2025 Mar 28;20(1):38. doi: 10.1186/s13024-025-00826-z.PMID: 40149017 

A Comprehensive Evaluation of Analytical Method Parameters Critical to the Reliable Assessment of Therapeutic mRNA Integrity by Capillary Gel Electrophoresis. Tran JP, Gao J, Lansdell C, Lorbetskie B, Johnston MJW, Wang L, Li X, Lu H.Electrophoresis. 2025 Mar 25. doi: 10.1002/elps.8123. Online ahead of print.PMID: 40130674

Colorectal Cancer: Pathogenesis and Targeted Therapy. Li J, Pan J, Wang L, Ji G, Dang Y.MedComm (2020). 2025 Mar 6;6(3):e70127. doi: 10.1002/mco2.70127. eCollection 2025 Mar.PMID: 40060193 

The ER-phagy receptor FAM134B is targeted by Salmonella Typhimurium to promote infection. Gatica D, Alsaadi RM, El Hamra R, Li B, Mueller R, Miyazaki M, Sun Q, Sad S, Russell RC. Nat Commun. 2025 Mar 25;16(1):2923. doi: 10.1038/s41467-025-58035-7.PMID: 40133256 

Entinostat, a histone deacetylase inhibitor, enhances CAR-NK cell anti-tumor activity by sustaining CAR expression. Jo DH, Kaczmarek S, Khan AUH, Pervin J, Clark DM, Gadde S, Wang L, McComb S, Visram A, Lee SH. Front Immunol. 2025 Mar 7;16:1533044. doi: 10.3389/fimmu.2025.1533044. eCollection 2025.PMID: 40124378 

Pain Trajectories in Pediatric Inflammatory Bowel Disease: Disease Severity, Optimism, and Pain Self-efficacy. Nabbijohn AN, Newby-Clark IR, Mack D, Stintzi A, McMurtry CM.Clin J Pain. 2025 Mar 7. doi: 10.1097/AJP.0000000000001279. Online ahead of print.PMID: 40052200

Campylobacter jejuni resistance to human milk involves the acyl carrier protein AcpP. Zhou B, Garber JM, Butcher J, Muszynski A, Casey RL, Huynh S, Archer-Hartmann S, Porfírio S, Rogers AM, Azadi P, Parker CT, Ng KKS, Hines KM, Stintzi A, Szymanski CM.mBio. 2025 Feb 25:e0399724. doi: 10.1128/mbio.03997-24. Online ahead of print.PMID: 39998218

Protocol for the purification and crystallization of the Drosophila melanogaster Cfp1PHD domain in complex with an H3K4me3 peptide. Grégoire S, Grégoire J, Joshi M, Capitani S, Chow S, Couture JF.STAR Protoc. 2025 Feb 21;6(1):103649. doi: 10.1016/j.xpro.2025.103649. Online ahead of print.PMID: 39985772

Plasma-derived protein and imaging biomarkers distinguish disease severity in oculopharyngeal muscular dystrophy. Smith IC, Sampaio ML, Melkus G, Meier-Ross K, Chakraborty S, Stotts C, Bourque PR, Lochmuller H, Brais B, Ayoub O, Perkins TJ, Khacho M, Warman-Chardon J.J Neuromuscul Dis. 2024 Dec 20:22143602241304990. doi: 10.1177/22143602241304990. Online ahead of print.PMID: 39973404

Nanoparticle-Mediated mRNA Delivery to Triple-Negative Breast Cancer (TNBC) Patient-Derived Xenograft (PDX) Tumors. El-Sahli S, Manturthi S, Durocher E, Bo Y, Akman A, Sannan C, Kirkby M, Iroakazi CD, Deyell H, Kaczmarek S,Lee SH, Iqbal U, Côté M, Wang L, Gadde S.ACS Pharmacol Transl Sci. 2025 Jan 24;8(2):460-469. doi: 10.1021/acsptsci.4c00597. eCollection 2025 Feb 14.PMID: 39974646

A hybrid machine learning framework for functional annotation of mitochondrial glutathione transport and metabolism proteins in cancers.Kennedy L, Sandhu JK, Harper ME, Cuperlovic-Culf M.BMC Bioinformatics. 2025 Feb 11;26(1):48. doi: 10.1186/s12859-025-06051-1.PMID: 39934670

Human milk extracellular vesicles modulate inflammation and cell survival in intestinal and immune cells.Vahkal B, Altosaar I, Ariana A, Jabbour J, Pantieras F, Daniel R, Tremblay É, Sad S, Beaulieu JF, Côté M, Ferretti E.Pediatr Res. 2024 Nov 28. doi: 10.1038/s41390-024-03757-5. Online ahead of print.PMID: 39609615

Antibiotic-mediated selection of randomly mutagenized and cytokine-expressing oncolytic viruses.Rezaei R, Boulton S, Ahmadi M, Petryk J, Da Silva M, Kooshki Zamani N, Singaravelu R, St-Laurent G, Daniel L, Sadeghipour A, Pelin A, Poutou J, Munoz Zuniga AI, Choy C, Gilchrist VH, Khalid Z, Austin B, Onsu KA, Marius R, Ameli Z, Mohammadi F, Mancinelli V, Wang E, Nik-Akhtar A, Alwithenani A, Panahi Arasi F, Ferguson SSG, Hobman TC, Alain T, Tai LH, Ilkow CS, Diallo JS, Bell JC, Azad T.Nat Biomed Eng. 2024 Nov 28. doi: 10.1038/s41551-024-01259-7. Online ahead of print.PMID: 39609558

Retinal Proteome Profiling of Inherited Retinal Degeneration Across Three Different Mouse Models Suggests Common Drug Targets in Retinitis Pigmentosa.Montaser AB, Gao F, Peters D, Vainionpää K, Zhibin N, Skowronska-Krawczyk D, Figeys D, Palczewski K, Leinonen H.Mol Cell Proteomics. 2024 Nov;23(11):100855. doi: 10.1016/j.mcpro.2024.100855. Epub 2024 Oct 9.PMID: 3938936

Clinical Microbiome Analysis by Mass Spectrometry-Based Metaproteomics.Zhang X, Ning Z, Mayne J, Figeys D.Annu Rev Anal Chem (Palo Alto Calif). 2025 Jan 15. doi: 10.1146/annurev-anchem-071124-113819. Online ahead of print.PMID: 39813733

The mutagenic properties of formaldehyde and acetaldehyde: Reflections on half a century of progress.Thapa MJ, Chan K.Mutat Res. 2024 Nov 8;830:111886. doi: 10.1016/j.mrfmmm.2024.111886. Online ahead of print.PMID: 39549522

Mitochondrial Dynamics Drive Muscle Stem Cell Progression from Quiescence to Myogenic Differentiation.Sommers O, Tomsine RA, Khacho M.Cells. 2024 Oct 26;13(21):1773. doi: 10.3390/cells13211773.PMID: 39513880

Dissecting immunological mechanisms underlying influenza viral nucleoprotein-induced mucosal immunity against diverse viral strains.Zhang W, Sloan A, Prévost J, Tamming L, Raman S, Pfeifle A, Gravel C, Chen W, Hashem AM, Wu J, Cao J, Johnston MJW, Wang L, Sauve S, Rosu-Myles M, Kobasa D, Safronetz D, Li X.Emerg Microbes Infect. 2024 Dec;13(1):2427792. doi: 10.1080/22221751.2024.2427792. Epub 2024 Nov 21.PMID: 39508450

Development of a riboflavin-responsive model of riboflavin transporter deficiency in zebrafish.Choueiri CM, Lau J, O'Connor E, DiBattista A, Wong BY, Spendiff S, Horvath R, Pena I, MacKenzie A, Lochmüller H.Hum Mol Genet. 2024 Dec 4:ddae171. doi: 10.1093/hmg/ddae171. Online ahead of print.PMID: 39656631

Identification of the Wnt signal peptide that directs secretion on extracellular vesicles.Gurriaran-Rodriguez U, Datzkiw D, Radusky LG, Esper M, Javandoost E, Xiao F, Ming H, Fisher S, Marina A, De Repentigny Y, Kothary R, Azkargorta M, Elortza F, Rojas AL, Serrano L, Hierro A, Rudnicki MA.Sci Adv. 2024 Dec 13;10(50):eado5914. doi: 10.1126/sciadv.ado5914. Epub 2024 Dec 11.PMID: 39661666 

Intrinsic Muscle Stem Cell Dysfunction Contributes to Impaired Regeneration in the mdx Mouse.Esper ME, Brun CE, Lin AYT, Feige P, Catenacci MJ, Sincennes MC, Ritso M, Rudnicki MA.J Cachexia Sarcopenia Muscle. 2025 Feb;16(1):e13682. doi: 10.1002/jcsm.13682.PMID: 39723578

Nanoparticles Codelivering mRNA and SiRNA for Simultaneous Restoration and Silencing of Gene/Protein Expression In Vitro and In Vivo.Manturthi S, El-Sahli S, Bo Y, Durocher E, Kirkby M, Popatia A, Mediratta K, Daniel R, Lee SH, Iqbal U, Côté M, Wang L, Gadde S.ACS Nanosci Au. 2024 Nov 15;4(6):416-425. doi: 10.1021/acsnanoscienceau.4c00040. eCollection 2024 Dec 18.PMID: 39713729 

MAGPIE: A Machine Learning Approach to Decipher Protein-Protein Interactions in Human Plasma. Hashimoto-Roth E, Forget D, Gaspar V, Bennett SAL, Gauthier MS, Coulombe B, Lavallée-Adam M.J Proteome Res. 2025 Jan 7. doi: 10.1021/acs.jproteome.4c00160. Online ahead of print.PMID: 39772751

Cisplatin exposure dysregulates insulin secretion in male and female mice.Basu L, Grieco-St-Pierre L, Ching MEA, Stead JDH, Hanson AA, Palaniyandi J, van Zyl EP, Hoyeck MP, McKay KS, van Allen KA, Lee H, Dai XQ, Bautista A, Fadzeyeva E, Mulvihill EE, Yauk CL, Mennigen JA, MacDonald PE, Bruin JE.Diabetes. 2025 Jan 14:db240419. doi: 10.2337/db24-0419. Online ahead of print.PMID: 39808439

A framework for understanding and investigating polyphosphate-protein interactions.McCarthy L, Baijal K, Downey M.Biochem Soc Trans. 2025 Jan 21:BST20240678. doi: 10.1042/BST20240678. Online ahead of print.PMID: 39836110

Mother's milk microbiota is associated with the developing gut microbial consortia in very-low-birth-weight infants.Shama S, Asbury MR, Kiss A, Bando N, Butcher J, Comelli EM, Copeland JK, Greco A, Kothari A, Sherman PM, Stintzi A, Taibi A, Tomlinson C, Unger S, Wang PW; OptiMoM Feeding Group; O'Connor DL.Cell Rep Med. 2024 Aug 31:101729. doi: 10.1016/j.xcrm.2024.101729. Online ahead of print.PMID: 39243753

Scalable Biomanufacturing Workflow to Produce and Isolate Natural Killer Cell-derived Extracellular Vesicle-based Cancer Biotherapeutics.St-Denis-Bissonnette F, Kirkby M, Wang L, Lavoie JR.J Vis Exp. 2024 Aug 16;(210). doi: 10.3791/67227.PMID: 39221940

Novel recombinant vaccinia virus-vectored vaccine affords complete protection against homologous Borrelia burgdorferi infection in mice.Pfeifle A, Zhang W, Cao J, Thulasi Raman SN, Anderson-Duvall R, Tamming L, Gravel C, Coatsworth H, Chen W, Johnston MJ, Sauve S, Rosu-Myles M, Wang L, Li X.Emerg Microbes Infect. 2024 Sep 2:2399949. doi: 10.1080/22221751.2024.2399949. Online ahead of print.PMID: 39221484

Copper homeostasis and cuproptosis in health and disease.Yang Y, Wu J, Wang L, Ji G, Dang Y.MedComm (2020). 2024 Sep 17;5(10):e724. doi: 10.1002/mco2.724. eCollection 2024 Oct.PMID: 39290254

Protocol to monitor live-cell, real-time, mitochondrial respiration in mouse muscle cells using the Resipher platform.Triolo M, Khacho M.STAR Protoc. 2024 Sep 20;5(4):103330. doi: 10.1016/j.xpro.2024.103330. Online ahead of print.PMID: 39305486

Lipid nanoparticle encapsulation of a Delta spike-CD40L DNA vaccine improves effectiveness against Omicron challenge in Syrian hamsters.Tamming L, Duque D, Tran A, Lansdell C, Frahm G, Wu J, Fekete EEF, Creskey M, Thulasi Raman SN, Laryea E, Zhang W, Pfeifle A, Gravel C, Stalker A, Hashem AM, Chen W, Stuible M, Durocher Y, Safronetz D, Cao J, Wang L, Sauve S, Rosu-Myles M, Zhang X, Johnston MJW, Li X.Mol Ther Methods Clin Dev. 2024 Aug 19;32(3):101325. doi: 10.1016/j.omtm.2024.101325. eCollection 2024 Sep 12.PMID: 39309757

GLP-1 receptor agonist-based and cardiovascular risk: a review of mechanisms.Mullur N, Morissette A, Morrow N, Mulvhill E.J Endocrinol. 2024 Aug 1:JOE-24-0046. doi: 10.1530/JOE-24-0046. Online ahead of print.PMID: 39145614

Astrocytes and the tumor microenvironment inflammatory state dictate the killing of glioblastoma cells by Smac mimetic compounds.Malone K, Dugas M, Earl N, Alain T, LaCasse EC, Beug ST.Cell Death Dis. 2024 Aug 15;15(8):592. doi: 10.1038/s41419-024-06971-5.PMID: 39147758

Multivariate analyses and machine learning link sex and age with antibody responses to SARS-CoV-2 and vaccination. Cuperlovic-Culf M, Bennett SAL, Galipeau Y, McCluskie PS, Arnold C, Bagheri S, Cooper CL, Langlois MA, Fritz JH, Piccirillo CA, Crawley AM.iScience. 2024 Jul 10;27(8):110484. doi: 10.1016/j.isci.2024.110484. eCollection 2024 Aug 16.PMID: 39156648

Leukemia inhibitory factor drives transcriptional programs that promote lipid accumulation and M2 polarization in macrophages.Chaparro V, Leroux LP, Lebourg A, Chagneau S, Graber TE, Alain T, Jaramillo M.J Leukoc Biol. 2024 Aug 23:qiae178. doi: 10.1093/jleuko/qiae178. Online ahead of print.PMID: 39178293

Complementary dual-virus strategy drives synthetic target and cognate T-cell engager expression for endogenous-antigen agnostic immunotherapy.Taha Z, Crupi MJF, Alluqmani N, MacKenzie D, Vallati S, Whelan JT, Fareez F, Alwithenani A, Petryk J, Chen A, Spinelli MM, Ng K, Sobh J, de Souza CT, Bharadwa PR, Lee TKH, Thomas DA, Huang BZ, Kassas O, Poutou J, Gilchrist VH, Boulton S, Thomson M, Marius R, Hooshyar M, McComb S, Arulanandam R, Ilkow CS, Bell JC, Diallo JS.

Metastatic breast cancer cells are metabolically reprogrammed to maintain redox homeostasis during metastasis.Biondini M, Lehuédé C, Tabariès S, Annis MG, Pacis A, Ma EH, Tam C, Hsu BE, Audet-Delage Y, Abu-Thuraia A, Girondel C, Sabourin V, Totten SP, de Sá Tavares Russo M, Bridon G, Avizonis D, Guiot MC, St-Pierre J, Ursini-Siegel J, Jones R, Siegel PM.Redox Biol. 2024 Jul 20;75:103276. doi: 10.1016/j.redox.2024.103276. Online ahead of print.PMID: 39053265

A qualitative evaluation of treatment fidelity alongside a pilot trial of a novel therapy for pediatric Inflammatory Bowel Disease.Olson JL, Castillo G, Palumbo A, Harrison M, Singleton R, Lalu MM, Fergusson DA, Stintzi A, Mack DR, Presseau J.PLoS One. 2024 Jul 30;19(7):e0292709. doi: 10.1371/journal.pone.0292709. eCollection 2024.PMID: 39078826

Loss of Dnajc21 leads to cytopenia and altered nucleotide metabolism in zebrafish.Ketharnathan S, Pokharel S, Prykhozhij SV, Cordeiro-Santanach A, Ban K, Dogan S, Hoang HD, Liebman MF, Leung E, Alain T, Alecu I, Bennett SAL, Čuperlović-Culf M, Dror Y, Berman JN.Leukemia. 2024 Aug 13. doi: 10.1038/s41375-024-02367-8. Online ahead of print.PMID: 39138265

Transcriptional regulation of the postnatal cardiac conduction system heterogeneity.Oh Y, Abid R, Dababneh S, Bakr M, Aslani T, Cook DP, Vanderhyden BC, Park JG, Munshi NV, Hui CC, Kim KH.Nat Commun. 2024 Aug 2;15(1):6550. doi: 10.1038/s41467-024-50849-1.PMID: 39095365

Regulation of Zfp36 by ISGF3 and MK2 restricts the expression of inflammatory cytokines during necroptosis stimulation.Yadav S, El Hamra R, Alturki NA, Ariana A, Bhan A, Hurley K, Gaestel M, Blackshear PJ, Blais A, Sad S.Cell Death Dis. 2024 Aug 8;15(8):574. doi: 10.1038/s41419-024-06964-4.PMID: 3911763

The E3 ubiquitin ligase Nedd4L preserves skeletal muscle stem cell quiescence by inhibiting their activation.Blackburn DM, Sahinyan K, Hernández-Corchado A, Lazure F, Richard V, Raco L, Perron G, Zahedi RP, Borchers CH, Lepper C, Kawabe H, Jahani-Asl A, Najafabadi HS, Soleimani VD.iScience. 2024 Jun 11;27(7):110241. doi: 10.1016/j.isci.2024.110241. eCollection 2024 Jul 19.PMID: 39015146

SMCHD1 activates the expression of genes required for the expansion of human myoblasts.Wong MM, Hachmer S, Gardner E, Runfola V, Arezza E, Megeney LA, Emerson CP Jr, Gabellini D, Dilworth FJ.Nucleic Acids Res. 2024 Jul 12:gkae600. doi: 10.1093/nar/gkae600. Online ahead of print.PMID: 38994563

Chromosome compaction is triggered by an autonomous DNA-binding module within condensin.Pastic A, Nosella ML, Kochhar A, Liu ZH, Forman-Kay JD, D'Amours D.Cell Rep. 2024 Jul 8;43(7):114419. doi: 10.1016/j.celrep.2024.114419. Online ahead of print.PMID: 38985672 

Structural insights into an atypical histone binding mechanism by a PHD finger.Grégoire S, Grégoire J, Yang Y, Capitani S, Joshi M, Sarvan S, Zaker A, Ning Z, Figeys D, Ulrich K, Brunzelle JS, Mer A, Couture JF.Structure. 2024 Jul 11:S0969-2126(24)00235-1. doi: 10.1016/j.str.2024.06.017. Online ahead of print.PMID: 39029460

Evaluation of resazurin phenoxazine dye as a highly sensitive cell viability potency assay for natural killer cell-derived extracellular vesicle-based cancer biotherapeutics.St-Denis-Bissonnette F, Qiu S, Cummings SE, Kirkby M, Haile Y, Wassmer S, Muradia G, Mehic J, Stalker A, Shrestha A, Ardolino M, Lee SH, BurgerD, Wang L, Lavoie JR.J Extracell Biol. 2024 Jul 17;3(7):e166. doi: 10.1002/jex2.166. eCollection 2024 Jul.PMID: 39022723

Repression of mRNA translation initiation by GIGYF1 via disrupting the eIF3-eIF4G1 interaction.Choi JH, Luo J, Hesketh GG, Guo S, Pistofidis A, Ladak RJ, An Y, Naeli P, Alain T, Schmeing TM, Gingras AC, Duchaine T, Zhang X, Sonenberg N, Jafarnejad SM.Sci Adv. 2024 Jul 19;10(29):eadl5638. doi: 10.1126/sciadv.adl5638. Epub 2024 Jul 17.PMID: 39018414 

Uncovering the Role of the Yeast Lysine Acetyltransferase NuA4 in the Regulation of Nuclear Shape and Lipid Metabolism.Laframboise SJ, Deneault LF, Denoncourt A, Downey M, Baetz K.Mol Cell Biol. 2024;44(7):273-288. doi: 10.1080/10985549.2024.2366206. Epub 2024 Jul 4.PMID: 38961766

Temperature-dependent Spike-ACE2 interaction of Omicron subvariants is associated with viral transmission.Benlarbi M, Ding S, Bélanger É, Tauzin A, Poujol R, Medjahed H, El Ferri O, Bo Y, Bourassa C, Hussin J, Fafard J, Pazgier M, Levade I, Abrams C, Côté M, Finzi A.mBio. 2024 Jul 2:e0090724. doi: 10.1128/mbio.00907-24. Online ahead of print.PMID: 38953636 

HumanIslets: An integrated platform for human islet data access and analysis.Ewald JD, Lu Y, Ellis CE, Worton J, Kolic J, Sasaki S, Zhang D, Dos Santos T, Spigelman AF, Bautista A, Dai XQ, Lyon JG, Smith NP, Wong JM, Rajesh V, Sun H, Sharp SA, Rogalski JC, Moravcova R, Cen HH, Manning Fox JE; HI-DAS Consortium; Atlas E, Bruin JE, Mulvihill EE, Verchere CB, Foster LJ, Gloyn AL, Johnson JD, Pepper AR, Lynn FC, Xia J, MacDonald PE.bioRxiv [Preprint]. 2024 Jun 22:2024.06.19.599613. doi: 10.1101/2024.06.19.599613.PMID: 38948734

Gestational age at birth influences protein and RNA content in human milk extracellular vesicles.Vahkal B, Altosaar I, Tremblay E, Gagné D, Hüttman N, Minic Z, Côté M, Blais A, Beaulieu JF, Ferretti E.J Extracell Biol. 2023 Dec 27;3(1):e128. doi: 10.1002/jex2.128. eCollection 2024 Jan.PMID: 38938674 

Obesity management for the treatment of type 2 diabetes: emerging evidence and therapeutic approaches.Morissette A, Mulvihill EE.J Pharm Pharm Sci. 2024 Jun 6;27:13065. doi: 10.3389/jpps.2024.13065. eCollection 2024.PMID: 38903652

Identification of an FMNL2 Interactome by Quantitative Mass Spectrometry.Fox S, Gaudreau-LaPierre A, Reshke R, Podinic I, Gibbings DJ, Trinkle-Mulcahy L, Copeland JW.Int J Mol Sci. 2024 May 23;25(11):5686. doi: 10.3390/ijms25115686.PMID: 38891874

Lasting differential gene expression of circulating CD8 T cells in chronic HCV infection with cirrhosis identifies a role for Hedgehog signaling in cellular hyperfunction.Li J, Vranjkovic A, Read D, Delaney SP, Stanford WL, Cooper CL, Crawley AM.Front Immunol. 2024 Jun 3;15:1375485. doi: 10.3389/fimmu.2024.1375485. eCollection 2024.PMID: 38887299 

PD-L1 promotes oncolytic virus infection via a metabolic shift that inhibits the type I IFN pathway.Hodgins JJ, Abou-Hamad J, O'Dwyer CE, Hagerman A, Yakubovich E, Tanese de Souza C, Marotel M, Buchler A, Fadel S, Park MM, Fong-McMaster C, Crupi MF, Makinson OJ, Kurdieh R, Rezaei R, Dhillon HS, Ilkow CS, Bell JC, Harper ME, Rotstein BH, Auer RC, Vanderhyden BC, Sabourin LA, Bourgeois-Daigneault MC, Cook DP, Ardolino M.J Exp Med. 2024 Jul 1;221(7):e20221721. doi: 10.1084/jem.20221721. Epub 2024 Jun 13.PMID: 38869480

AMPK-mediated regulation of endogenous cholesterol synthesis does not affect atherosclerosis in a murine Pcsk9-AAV model.Smith TKT, Ghorbani P, LeBlond ND, Nunes JRC, O'Dwyer C, Ambursley N, Fong-McMaster C, Minarrieta L, Burkovsky LA, El-Hakim R, Trzaskalski NA, Locatelli CAA, Stotts C, Pember C, Rayner KJ, Kemp BE, Loh K, Harper ME, Mulvihill EE, St-Pierre J, Fullerton MD.Atherosclerosis. 2024 Jun 3:117608. doi: 10.1016/j.atherosclerosis.2024.117608. Online ahead of print.PMID: 38880706

Pairing metagenomics and metaproteomics to characterize ecological niches and metabolic essentiality of gut microbiomes.Wang T, Li L, Figeys D, Liu YY.ISME Commun. 2024 May 1;4(1):ycae063. doi: 10.1093/ismeco/ycae063. eCollection 2024 Jan.PMID: 38808120 

Spectral entropy as a measure of the metaproteome complexity.Duan H, Ning Z, Zhang A, Figeys D.Proteomics. 2024 May 25:e2300570. doi: 10.1002/pmic.202300570. Online ahead of print.PMID: 38794877

RapidAIM 2.0: a high-throughput assay to study functional response of human gut microbiome to xenobiotics.Li L, Mayne J, Beltran A, Zhang X, Ning Z, Figeys D.Microbiome Res Rep. 2024 Apr 3;3(2):26. doi: 10.20517/mrr.2023.57. eCollection 2024.PMID: 38841404

Cystine/glutamate antiporter xCT controls skeletal muscle glutathione redox, bioenergetics and differentiation.Kanaan MN, Pileggi CA, Karam CY, Kennedy LS, Fong-McMaster C, Cuperlovic-Culf M, Harper ME.Redox Biol. 2024 May 25;73:103213. doi: 10.1016/j.redox.2024.103213. Online ahead of print.PMID: 38815331

Multilevel Proteomic Profiling of Colorectal Adenocarcinoma Caco-2 Cell Differentiation to Characterize an Intestinal Epithelial Model.Fekete EE, Wang A, Creskey M, Cummings SE, Lavoie JR, Ning Z, Li J, Figeys D, Chen R, Zhang X.J Proteome Res. 2024 May 29. doi: 10.1021/acs.jproteome.4c00276. Online ahead of print.PMID: 38810023

Myokine Secretion following an Aerobic Exercise Intervention in Individuals with Type 2 Diabetes with or without Exercise Resistance.Garneau L, Mulvihill EE, Smith SR, Sparks LM, Aguer C.Int J Mol Sci. 2024 Apr 30;25(9):4889. doi: 10.3390/ijms25094889.PMID: 38732106 

Editorial: Application of genomics and epigenetics in disease and syndrome classification.Dang Y, Wang W, Lyu A, Wang L, Ji G.Front Genet. 2024 May 1;15:1421163. doi: 10.3389/fgene.2024.1421163. eCollection 2024.PMID: 38752183

The integrated stress response promotes neural stem cell survival under conditions of mitochondrial dysfunction in neurodegeneration.Iqbal MA, Bilen M, Liu Y, Jabre V, Fong BC, Chakroun I, Paul S, Chen J, Wade S, Kanaan M, Harper ME, Khacho M, Slack RS. Aging Cell. 2024 May 16:e14165. doi: 10.1111/acel.14165. Online ahead of print.PMID: 38757355 

Myeloid AMPK signaling restricts fibrosis but is not required for metformin improvements during CDAHFD-induced NASH in mice.Nunes JRC, O'Dwyer C, Ghorbani P, Smith TKT, Chauhan S, Robert-Gostlin V, Girouard MD, Viollet B, Foretz M, Fullerton MD.J Lipid Res. 2024 May 16:100564. doi: 10.1016/j.jlr.2024.100564. Online ahead of print.PMID: 38762124

A Deep Learning Approach to Predict Bleeding Risk Over Time in Patients on Extended Anticoagulation Therapy.Shahryari Fard S, Perkins TJ, Wells PS.J Thromb Haemost. 2024 Apr 18:S1538-7836(24)00219-8. doi: 10.1016/j.jtha.2024.04.005. Online ahead of print.PMID: 38642704

The Landscape and Perspectives of the Human Gut Metaproteomics.Sun Z, Ning Z, Figeys D.Mol Cell Proteomics. 2024 Apr 10:100763. doi: 10.1016/j.mcpro.2024.100763. Online ahead of print.PMID: 38608842

Targeting CD73 with flavonoids inhibits cancer stem cells and increases lymphocyte infiltration in a triple-negative breast cancer mouse model.Mediratta K, El-Sahli S, Marotel M, Awan MZ, Kirkby M, Salkini A, Kurdieh R, Abdisalam S, Shrestha A, Di Censo C, Sulaiman A, McGarry S, Lavoie JR, Liu Z, Lee SH, Li X, Sciumè G, D'Costa VM, Ardolino M, Wang L.Front Immunol. 2024 Mar 27;15:1366197. doi: 10.3389/fimmu.2024.1366197. eCollection 2024.PMID: 38601156

Polyphosphate kinase regulates LPS structure and polymyxin resistance during starvation in E. coli.Baijal K, Abramchuk I, Herrera CM, Mah TF, Trent MS, Lavallée-Adam M, Downey M.PLoS Biol. 2024 Mar 13;22(3):e3002558. doi: 10.1371/journal.pbio.3002558. Online ahead of print.PMID: 38478588

A topographical atlas of α-synuclein dosage and cell type-specific expression in adult mouse brain and peripheral organs.Geertsma HM, Fisk ZA, Sauline L, Prigent A, Kurgat K, Callaghan SM; aSCENT-PD Consortium; Henderson MX, Rousseaux MWC.NPJ Parkinsons Dis. 2024 Mar 19;10(1):65. doi: 10.1038/s41531-024-00672-8.PMID: 38504090 Free

Characterization of the diversity of type IV secretion system-encoding plasmids in Acinetobacter.Nasser F, Gaudreau A, Lubega S, Zaker A, Xia X, Mer AS, D'Costa VM.Emerg Microbes Infect. 2024 Dec;13(1):2320929. doi: 10.1080/22221751.2024.2320929. Epub 2024 Mar 26.PMID: 3853096

Immunomodulation and inflammation: Role of GLP-1R and GIPR expressing cells within the gut.Morrow NM, Morissette A, Mulvihill EE.Peptides. 2024 Mar 28;176:171200. doi: 10.1016/j.peptides.2024.171200. Online ahead of print.PMID: 38555054 

PINK1 deficiency alters muscle stem cell fate decision and muscle regenerative capacity.Cairns G, Thumiah-Mootoo M, Abbasi MR, Gourlay M, Racine J, Larionov N, Prola A, Khacho M, Burelle Y.Stem Cell Reports. 2024 Mar 26:S2213-6711(24)00079-1. doi: 10.1016/j.stemcr.2024.03.004. Online ahead of print.PMID: 38579709

Single-Cell RNA Sequencing Reveals Repair Features of Human Umbilical Cord Mesenchymal Stromal Cells.Cyr-Depauw C, Cook DP, Mižik I, Lesage F, Vadivel A, Renesme L, Deng Y, Zhong S, Bardin P, Xu L, Möbius MA, Marzahn J, Freund D, Stewart DJ, Vanderhyden BC, Rüdiger M, Thébaud B.Am J Respir Crit Care Med. 2024 Apr 2. doi: 10.1164/rccm.202310-1975OC. Online ahead of print.PMID: 38564376

Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy.Parmasad JA, Ricke KM, Nguyen B, Stykel MG, Buchner-Duby B, Bruce A, Geertsma HM, Lian E, Lengacher NA, Callaghan SM, Joselin A, Tomlinson JJ, Schlossmacher MG, Stanford WL, Ma J, Brundin P, Ryan SD, Rousseaux MWC.Cell Death Dis. 2024 Apr 4;15(4):246. doi: 10.1038/s41419-024-06534-8.PMID: 38575601 

Progeria-based vascular model identifies networks associated with cardiovascular aging and disease.Ngubo M, Chen Z, McDonald D, Karimpour R, Shrestha A, Yockell-Lelièvre J, Laurent A, Besong OTO, Tsai EC, Dilworth FJ, Hendzel MJ, Stanford WL.Aging Cell. 2024 Apr 4:e14150. doi: 10.1111/acel.14150. Online ahead of print.PMID: 38576084

Glycomacropeptide as an Efficient Agent to Fight Pathophysiological Mechanisms of Metabolic Syndrome.Sauvé MF, Feldman F, Sané AT, Koudoufio M, Patey N, Spahis S, Butcher J, Duan H, Figeys D, Marcil V, Stintzi A, Levy E.Nutrients. 2024 Mar 17;16(6):871. doi: 10.3390/nu16060871.PMID: 38542783 

PHF6-mediated transcriptional control of NSC via Ephrin receptors is impaired in the intellectual disability syndrome BFLS.Rasool D, Burban A, Sharanek A, Madrigal A, Hu J, Yan K, Qu D, Voss AK, Slack RS, Thomas T, Bonni A, Picketts DJ, Soleimani VD, Najafabadi HS, Jahani-Asl A. EMBO Rep. 2024 Mar 1. doi: 10.1038/s44319-024-00082-0. Online ahead of print.PMID: 38429579

CIAO1 and MMS19 deficiency: a lethal neurodegenerative phenotype caused by cytosolic Fe-S cluster protein assembly disorders.van Karnebeek CDM, Tarailo-Graovac M, Leen R, Meinsma R, Correard S, Jansen-Meijer J, Prykhozhij SV, Pena IA, Ban K, Schock S, Saxena V, Pras-Raves ML, Drögemöller BI, Grootemaat AE, van der Wel NN, Dobritzsch D, Roseboom W, Schomakers BV, Jaspers YRJ, Zoetekouw L, Roelofsen J, Ferreira CR, van der Lee R, Ross CJ, Kochan J, McIntyre RL, van Klinken JB, van Weeghel M, Kramer G, Weschke B, Labrune P, Willemsen MA, Riva D, Garavaglia B, Moeschler JB, Filiano JJ, Ekker M, Berman JN, Dyment D, Vaz FM, Wassermann WW, Houtkooper RH, van Kuilenburg ABP.Genet Med. 2024 Feb 24:101104. doi: 10.1016/j.gim.2024.101104. Online ahead of print.PMID: 38411040

MicroRNA205: A Key Regulator of Cardiomyocyte Transition from Proliferative to Hypertrophic Growth in the Neonatal Heart.Weldrick JJ, Yi R, Megeney LA, Burgon PG.Int J Mol Sci. 2024 Feb 12;25(4):2206. doi: 10.3390/ijms25042206.PMID: 38396885

Optic atrophy 1 mediates muscle differentiation by promoting a metabolic switch via the supercomplex assembly factor SCAF1.Triolo M, Baker N, Agarwal S, Larionov N, Podinić T, Khacho M.iScience. 2024 Feb 9;27(3):109164. doi: 10.1016/j.isci.2024.109164. eCollection 2024 Mar 15.PMID: 38414856

The SMC5/6 complex: folding chromosomes back into shape when genomes take a break.Roy S, Adhikary H, D'Amours D.Nucleic Acids Res. 2024 Feb 20:gkae103. doi: 10.1093/nar/gkae103. Online ahead of print.PMID: 38375830

The Complexities of Intestinal Lipoprotein Production in Insulin Resistance and Diabetes: Revisiting a 2010 Diabetes Classic by Pavlic et al. Lewis GF, Mulvihill EE.Diabetes. 2024 Mar 1;73(3):335-337. doi: 10.2337/dbi23-0036.PMID: 38377446

p66ShcA promotes malignant breast cancer phenotypes by alleviating energetic and oxidative stress.Lewis K, La Selva R, Maldonado E, Annis MG, Najyb O, Cepeda Cañedo E, Totten S, Hébert S, Sabourin V, Mirabelli C, Ciccolini E, Lehuédé C, Choinière L, Russo M, Avizonis D, Park M, St-Pierre J, Kleinman CL, Siegel PM, Ursini-Siegel J.Redox Biol. 2024 Jan 5;70:103028. doi: 10.1016/j.redox.2024.103028. Online ahead of print.PMID: 38211442

Empirical Bayes single nucleotide variant-calling for next-generation sequencing data.Karimnezhad A, Perkins TJ.Sci Rep. 2024 Jan 18;14(1):1550. doi: 10.1038/s41598-024-51958-z.PMID: 38233494

The aryl hydrocarbon receptor in β-cells mediates the effects of TCDD on glucose homeostasis in mice.Hoyeck MP, Angela Ching ME, Basu L, van Allen K, Palaniyandi J, Perera I, Poleo-Giordani E, Hanson AA, Ghorbani P, Fullerton MD, Bruin JE.Mol Metab. 2024 Feb 2;81:101893. doi: 10.1016/j.molmet.2024.101893. Online ahead of print.PMID: 38309623 

NLRC5 overexpression in ovarian tumors remodels the tumor microenvironment and increases T-cell reactivity toward autologous tumor-associated antigens.Rodriguez GM, Yakubovich E, Murshed H, Maranda V, Galpin KJC, Cudmore A, Hanna AMR, Macdonald E, Ramesh S, Garson K, Vanderhyden BC.Front Immunol. 2024 Jan 3;14:1295208. doi: 10.3389/fimmu.2023.1295208. eCollection 2023.PMID: 38235131

Wnt7a is Required for Regeneration of Dystrophic Skeletal Muscle.Gurriaran-Rodriguez U, Kodippili K, Datzkiw D, Javandoost E, Xiao F, Rejas MT, Rudnicki MA.bioRxiv. 2024 Jan 25:2024.01.24.577041. doi: 10.1101/2024.01.24.577041. Preprint.PMID: 38328077

Sialyl LewisX glycomimetics bearing an extended anionic chain targeting E- and P- selectin binding sites.Belouin A, Simard RD, Joyal M, Maharsy W, Lau A, Prévost M, Nemer M, Guindon Y.Bioorg Med Chem. 2023 Dec 9;98:117553. doi: 10.1016/j.bmc.2023.117553. Online ahead of print.PMID: 38128297

FGL2 promotes tumour growth and attenuates infiltration of activated immune cells in melanoma and ovarian cancer models.Galpin KJC, Rodriguez GM, Maranda V, Cook DP, Macdonald E, Murshed H, Zhao S, McCloskey CW, Chruscinski A, Levy GA, Ardolino M, Vanderhyden BC.Sci Rep. 2024 Jan 8;14(1):787. doi: 10.1038/s41598-024-51217-1.PMID: 38191799

Sox10-Deficient Drug-Resistant Melanoma Cells Are Refractory to Oncolytic RNA Viruses.Abou-Hamad J, Hodgins JJ, Yakubovich E, Vanderhyden BC, Ardolino M, Sabourin LA.Cells. 2023 Dec 29;13(1):73. doi: 10.3390/cells13010073.PMID: 38201278

Accessory subunit NDUFB4 participates in mitochondrial complex I supercomplex formationParmar G, Fong-McMaster C, Pileggi C, Patten DA, Cuillerier A, Myers S, Wang Y, Hekimi S, Cuperlovic-Culf M, Harper M-E. Journal of Biological Chemistry 2024. 105626

High-Pressure Delivery of Oncolytic Viruses via Needle-Free Injection Preserves Therapeutic Activity.Said A, Hoang HD, Earl N, Xiang X, Siddiqui N, Côté M, Alain T.Cancers (Basel). 2023 Nov 30;15(23):5655. doi: 10.3390/cancers15235655.PMID: 38067359

Unveiling the Immunogenicity of Ovarian Tumors as the Crucial Catalyst for Therapeutic Success.Rodriguez GM, Yakubovich E, Vanderhyden BC.Cancers (Basel). 2023 Dec 2;15(23):5694. doi: 10.3390/cancers15235694.PMID: 38067396

Mesenchymal ovarian cancer cells promote CD8+ T cell exhaustion through the LGALS3-LAG3 axis.Yakubovich E, Cook DP, Rodriguez GM, Vanderhyden BC.NPJ Syst Biol Appl. 2023 Dec 12;9(1):61. doi: 10.1038/s41540-023-00322-4.PMID: 38086828

The microbiome of two strategies for ammonia removal with the sequencing batch moving bed biofilm reactor treating cheese production wastewater.Tsitouras A, Al-Ghussain N, Butcher J, Stintzi A, Delatolla R.Appl Environ Microbiol. 2023 Nov 27:e0150723. doi: 10.1128/aem.01507-23. Online ahead of print.PMID: 38009922

BRCA1 and BRCA2 deficient tumour models generate distinct ovarian tumour microenvironments and differential responses to therapy.Farokhi Boroujeni S, Rodriguez G, Galpin K, Yakubovich E, Murshed H, Ibrahim D, Asif S, Vanderhyden BC.J Ovarian Res. 2023 Nov 28;16(1):231. doi: 10.1186/s13048-023-01313-z.PMID: 38017453 

CARM1 drives mitophagy and autophagy flux during fasting-induced skeletal muscle atrophy.Stouth DW, vanLieshout TL, Mikhail AI, Ng SY, Raziee R, Edgett BA, Vasam G, Webb EK, Gilotra KS, Markou M, Pineda HC, Bettencourt-Mora BG, Noor H, Moll Z, Bittner ME, Gurd BJ, Menzies KJ, Ljubicic V.Autophagy. 2023 Nov 29. doi:

The SARS-CoV-2 spike glycoprotein interacts with MAO-B and impairs mitochondrial energetics.Pileggi CA, Parmar G, Elkhatib H, Stewart CM, Alecu I, Côté M, Bennett SAL, Sandhu JK, Cuperlovic-Culf M, Harper ME.Curr Res Neurobiol. 2023 Oct 6;5:100112. doi: 10.1016/j.crneur.2023.100112. eCollection 2023.PMID: 38020812

Macrophage AMPK β1 activation by PF-06409577 reduces the inflammatory response, cholesterol synthesis, and atherosclerosis in mice.Day EA, Townsend LK, Rehal S, Batchuluun B, Wang D, Morrow MR, Lu R, Lundenberg L, Lu JH, Desjardins EM, Smith TKT, Raphenya AR, McArthur AG, Fullerton MD, Steinberg GR.iScience. 2023 Oct 20;26(11):108269. doi: 10.1016/j.isci.2023.108269. eCollection 2023 Nov 17.PMID: 38026185

Extracellular vesicle storm during the course of Ebola virus infection in primates.Vucetic A, Lafleur A, Côté M, Kobasa D, Chan M, Alvarez F, Piccirillo C, Dong G, Olivier M.Front Cell Infect Microbiol. 2023 Nov 15;13:1275277. doi: 10.3389/fcimb.2023.1275277. eCollection 2023.PMID: 38035334

CLIC1 regulation of cancer stem cells in glioblastoma.Randhawa K, Jahani-Asl A.Curr Top Membr. 2023;92:99-123. doi: 10.1016/bs.ctm.2023.09.004. Epub 2023 Sep 29.PMID: 38007271

A clinically relevant large-scale biomanufacturing workflow to produce natural killer cells and natural killer cell-derived extracellular vesicles for cancer immunotherapy.St-Denis-Bissonnette F, Cummings SE, Qiu S, Stalker A, Muradia G, Mehic J, Mediratta K, Kaczmarek S, Burger D, Lee SH, Wang L, Lavoie JR.J Extracell Vesicles. 2023 Dec;12(12):e12387. doi: 10.1002/jev2.12387.PMID: 38054534

Editorial: Reviews and advances in our understanding of the relationship between the cell cycle, DNA damage and cancer.D'Amours D.Front Cell Dev Biol. 2023 Nov 16;11:1333628. doi: 10.3389/fcell.2023.1333628. eCollection 2023.PMID: 38046669

Comparative analysis of syngeneic mouse models of high-grade serous ovarian cancer. Cook DP, Galpin KJC, Rodriguez GM, Shakfa N, Wilson-Sanchez J, Echaibi M, Pereira M, Matuszewska K, Haagsma J, Murshed H, Cudmore AO, MacDonald E, Tone A, Shepherd TG, Petrik JJ, Koti M, Vanderhyden BC.Commun Biol. 2023 Nov 13;6(1):1152. doi: 10.1038/s42003-023-05529-z.PMID: 37957414

Tissue-Specific Tumour Suppressor and Oncogenic Activities of the Polycomb-like Protein MTF2.Ngubo M, Moradi F, Ito CY, Stanford WL.Genes (Basel). 2023 Sep 27;14(10):1879. doi: 10.3390/genes14101879.PMID: 37895228

The Expression Kinetics and Immunogenicity of Lipid Nanoparticles Delivering Plasmid DNA and mRNA in Mice.Zhang W, Pfeifle A, Lansdell C, Frahm G, Cecillon J, Tamming L, Gravel C, Gao J, Thulasi Raman SN, Wang L, Sauve S, Rosu-Myles M, Li X, Johnston MJW.Vaccines (Basel). 2023 Oct 11;11(10):1580. doi: 10.3390/vaccines11101580.PMID: 37896985

The SARS-CoV-2 spike glycoprotein interacts with MAO-B and impairs mitochondrial energeticsChantal A. Pileggi a b c, Gaganvir Parmar a b, Hussein Elkhatib a b, Corina M. Stewart a b d, Irina Alecu a b e, Marceline Côté a b f, Steffany A.L. Bennett a b e, Jagdeep K. Sandhu a b f g, Miroslava Cuperlovic-Culf a b c 1, Mary-Ellen Harper a b f 1. Received 14 March 2023, Revised 21 August 2023, Accepted 25 September 2023, Available online 6 October 2023, Version of Record 14 October 2023. https://doi.org/10.1016/j.crneur.2023.100112

The Potential of Hormonal Therapies for Treatment of Triple-Negative Breast Cancer.Kirkby M, Popatia AM, Lavoie JR, Wang L.Cancers (Basel). 2023 Sep 24;15(19):4702. doi: 10.3390/cancers15194702.PMID: 37835396 

A comparison of rat models that best mimic immune-driven preeclampsia in humans.Jahan F, Vasam G, Cariaco Y, Nik-Akhtar A, Green A, Menzies KJ, Bainbridge SA.Front Endocrinol (Lausanne). 2023 Sep 28;14:1219205. doi: 10.3389/fendo.2023.1219205. eCollection 2023.PMID: 37842294 

Staufen1 controls mitochondrial metabolism via HIF2α in embryonal rhabdomyosarcoma and promotes tumorigenesis.Almasi S, SarmastiEmami S, Baird S, Ning Z, Figeys D, Côté J, Cowan KN, Jasmin BJ.Cell Mol Life Sci. 2023 Oct 17;80(11):328. doi: 10.1007/s00018-023-04969-4.PMID: 37847286

Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages.Kim H, Aliar K, Tharmapalan P, McCloskey CW, Kuttanamkuzhi A, Grünwald BT, Palomero L, Mahendralingam MJ, Waas M, Mer AS, Elliott MJ, Zhang B, Al-Zahrani KN, Langille ER, Parsons M, Narala S, Hofer S, Waterhouse PD, Hakem R, Haibe-Kains B, Kislinger T, Schramek D, Cescon DW, Pujana MA, Berman HK, Khokha R

Mitochondrial Fragmentation Promotes Inflammation Resolution Responses in Macrophages via Histone Lactylation.Susser LI, Nguyen MA, Geoffrion M, Emerton C, Ouimet M, Khacho M, Rayner KJ.Mol Cell Biol. 2023;43(10):531-546. doi: 10.1080/10985549.2023.2253131. Epub 2023 Oct 11.PMID: 37807652 

Pevonedistat, a First in-class NEDD8-activating Enzyme Inhibitor, sensitizes cancer cells to VSVΔ51 Oncolytic Virotherapy.Wong B, Bergeron A, Maznyi G, Ng K, Jirovec A, Birdi HK, Serrano D, Spinelli M, Thomson M, Taha Z, Alwithenani A, Chen A, Lorimer I, Vanderhyden B, Arulanandam R, Diallo JS.Mol Ther. 2023 Sep 27:S1525-0016(23)00504-X. doi: 10.1016/j.ymthe.2023.09.017. Online ahead of print.PMID: 37766429

Humoral Responses Elicited after a Fifth Dose of SARS-CoV-2 mRNA Bivalent Vaccine.Tauzin A, Beaudoin-Bussières G, Benlarbi M, Nayrac M, Bo Y, Gendron-Lepage G, Medjahed H, Perreault J, Gokool L, Arlotto P, Morrisseau C, Tremblay C, Kaufmann DE, Martel-Laferrière V, Levade I, Côté M, Bazin R, Finzi A.

Choline metabolism underpins macrophage IL-4 polarization and RELMα up-regulation in helminth infection.Ghorbani P, Kim SY, Smith TKT, Minarrieta L, Robert-Gostlin V, Kilgour MK, Ilijevska M, Alecu I, Snider SA, Margison KD, Nunes JRC, Woo D, Pember C, O'Dwyer C, Ouellette J, Kotchetkov P, St-Pierre J, Bennett SAL, Lacoste B, Blais A, Nair MG, Fullerton MD.PLoS Pathog. 2023 Sep 25;19(9):e1011658. doi: 10.1371/journal.ppat.1011658. Online ahead of print.PMID: 37747879

A Versatile Strategy for Genetic Manipulation of Cajal-Retzius Cells in the Adult Mouse Hippocampus.van Bruggen R, Patel ZH, Wang M, Suk TR, Rousseaux MWC, Tan Q.eNeuro. 2023 Sep 29:ENEURO.0054-23.2023. doi: 10.1523/ENEURO.0054-23.2023. Online ahead of print.PMID: 37775311

KIT D816V is dimerization-independent and activates downstream pathways frequently perturbed in mastocytosis.Rajan V, Prykhozhij SV, Pandey A, Cohen AM, Rainey JK, Berman JN. Br J Haematol. 2023 Sep;202(5):960-970. doi: 10.1111/bjh.18116. Epub 2022 Mar 4. PMID: 35245395

Modification of histidine repeat proteins by inorganic polyphosphate.Neville N, Lehotsky K, Yang Z, Klupt KA, Denoncourt A, Downey M, Jia Z.Cell Rep. 2023 Sep 1;42(9):113082. doi: 10.1016/j.celrep.2023.113082. Online ahead of print.PMID: 37660293

Mutation Knock-in Methods Using Single-Stranded DNA and Gene Editing Tools in Zebrafish.Mutation Knock-in Methods Using Single-Stranded DNA and Gene Editing Tools in Zebrafish. Prykhozhij SV, Berman JN.Methods Mol Biol. 2024;2707:279-303. doi: 10.1007/978-1-0716-3401-1_19.PMID: 37668920

Radiation induces long-term muscle fibrosis and promotes a fibrotic phenotype in fibro-adipogenic progenitorsNicolas Collao, Donna D'Souza, Laura Messeiller, Evan Pilon, Jessica Lloyd, Jillian Larkin, Matthew Ngu, Alexanne Cuillerier, Alexander E. Green, Keir J. Menzies, Yan Burelle, Michael De LisioFirst published: 06 September 2023 https://doi.org/10.1002/jcsm.13320

MetaPep: A core peptide database for faster human gut metaproteomics database searches.Sun Z, Ning Z, Cheng K, Duan H, Wu Q, Mayne J, Figeys D.Comput Struct Biotechnol J. 2023 Aug 29;21:4228-4237. doi: 10.1016/j.csbj.2023.08.025. eCollection 2023.PMID: 37692080

The Regulation and Immune Signature of Retrotransposons in Cancer.Alkailani MI, Gibbings D.Cancers (Basel). 2023 Aug 30;15(17):4340. doi: 10.3390/cancers15174340.PMID: 37686616

Generation of the human iPSC lines AKOSi011-A carrying the mutation p.Pro65Ser/p.Asp35T and AKOSi012-A, carrying the mutation p.Tyr231His, derived from FAHN patient fibroblasts. Efendic F, Krohn S, Murua Escobar H, Venkateswaran S, Bennett SAL, Hermann A, Frech MJ.Stem Cell Res. 2023 Aug 9;71:103178. doi: 10.1016/j.scr.2023.103178. Online ahead of print. PMID: 37573804

Conventional DNA-Damaging Cancer Therapies and Emerging cGAS-STING Activation: A Review and Perspectives Regarding Immunotherapeutic Potential.Lewicky JD, Martel AL, Gupta MR, Roy R, Rodriguez GM, Vanderhyden BC, Le HT.Cancers (Basel). 2023 Aug 16;15(16):4127. doi: 10.3390/cancers15164127.PMID: 37627155

Caspase 3 exhibits a yeast metacaspase proteostasis function that protects mitochondria from toxic TDP43 aggregates.Brunette S, Sharma A, Bell R, Puente L, Megeney LA.Microb Cell. 2023 Jul 10;10(8):157-169. doi: 10.15698/mic2023.08.801. eCollection 2023 Aug 7.PMID: 37545643 

The TNFα/TNFR2 axis mediates natural killer cell proliferation by promoting aerobic glycolysisKhan AUH, Ali AK, Marr B, Jo D, Ahmadvand S, Fong-McMaster C, Almutairi SM, Wang L, Sad S, Harper ME, Lee SH. Cell Mol Immunol. 2023 Aug 9. doi: 10.1038/s41423-023-01071-4. Online ahead of print.PMID: 37553427

Comprehensive interrogation of human skeletal muscle reveals a dissociation between insulin resistance and mitochondrial capacity.Whytock KL, Pino MF, Sun Y, Yu G, De Carvalho FG, Yeo RX, Vega RB, Gaganvir P, Divoux A, Kapoor N, Yi F, Cornnell HH, Patten DA, Harper ME, Gardell SJ, Smith SR, Walsh MJ, Sparks LM.Am J Physiol Endocrinol Metab. 2023 Aug 16. doi: 10.1152/ajpendo.00143.2023. Online ahead of print.PMID: 37584609

The Influence of Protein Secretomes of Enterococcus durans on ex vivo Human Gut Microbiome.Comerlato CB, Zhang X, Walker K, Mayne J, Figeys D, Brandelli A.Probiotics Antimicrob Proteins. 2023 Aug 17. doi: 10.1007/s12602-023-10136-9. Online ahead of print.PMID: 37589783
 

Synthesis of Sialyl LewisX Mimetics with E- and P-Selectin Binding Properties and Immunosuppressive Activity. Simard RD, Joyal M, Beaugrand T, Gauthier J, Hardine E, Desriac A, Buffet CH, Prévost M, Nemer M, Guindon Y. J Org Chem. 2023 Aug 4;88(15):10974-10985. doi: 10.1021/acs.joc.3c00956. Epub 2023 Jul 14. PMID: 37449872

Development of a V5-tag-directed nanobody and its implementation as an intracellular biosensor of GPCR signalling.Zeghal M, Matte K, Venes A, Patel S, Laroche G, Sarvan S, Joshi M, Rain JC, Couture JF, Giguère PM.J Biol Chem. 2023 Jul 28:105107. doi: 10.1016/j.jbc.2023.105107. Online ahead of print.PMID: 37517699 

Ketone Ester Administration Improves Glycemia in Obese Mice.Tabatabaei Dakhili SA, Yang K, Locatelli CAA, Saed CT, Greenwell AA, Chan JSF, Chahade JJ, Scharff J, Al Imarah S, Eaton F, Crawford PA, Gopal K, Mulvihill EE, Ussher JR.Am J Physiol Cell Physiol. 2023 Aug 14. doi: 10.1152/ajpcell.00300.2023. Online ahead of print.PMID: 37575059

Signed distance correlation (SiDCo): an online implementation of distance correlation and partial distance correlation for data-driven network analysis. Monti F, Stewart D, Surendra A, Alecu I, Nguyen-Tran T, Bennett SAL, Čuperlović-Culf M. Bioinformatics. 2023 May 3:btad210. doi: 10.1093/bioinformatics/btad210. Online ahead of print. PMID: 37137236

16p11.2 haploinsufficiency reduces mitochondrial biogenesis in brain endothelial cells and alters brain metabolism in adult mice.Béland-Millar A, Kirby A, Truong Y, Ouellette J, Yandiev S, Bouyakdan K, Pileggi C, Naz S, Yin M, Carrier M, Kotchetkov P, St-Pierre MK, Tremblay MÈ, Courchet J, Harper ME, Alquier T, Messier C, Shuhendler AJ, Lacoste B. Cell Rep. 2023 May 6;42(5):112485. doi: 10.1016/j.celrep.2023.112485. Online ahead of print.PMID: 37149866 

Novel Homozygous Variant in COQ7 in Siblings With Hereditary Motor Neuropathy. Smith IC, Pileggi CA, Wang Y, Kernohan K, Hartley T, McMillan HJ, Sampaio ML, Melkus G, Woulfe J, Parmar G, Bourque PR, Breiner A, Zwicker J, Pringle CE, Jarinova O, Lochmüller H, Dyment DA, Brais B, Boycott KM; Care4Rare Canada Consortium,; Hekimi S, Harper ME, Warman-Chardon J. Neurol Genet. 2023 Jan 25;9(1):e200048. doi: 10.1212/NXG.0000000000200048. eCollection 2023 Feb.

Simultaneous engineering of natural killer cells for CAR transgenesis and CRISPR-Cas9 knockout using retroviral particles. Jo DH, Kaczmarek S, Shin O, Wang L, Cowan J, McComb S, Lee SH. Mol Ther Methods Clin Dev. 2023 Mar 15;29:173-184. doi: 10.1016/j.omtm.2023.03.006. eCollection 2023 Jun 8. PMID: 37063482

Differences in Sex-Specific Frequency of Glucocerebrosidase Variant Carriers and Familial Parkinsonism. Ortega RA, Bressman SB, Raymond D, Ozelius LJ, Wang C, Bennett SAL, Saunders-Pullman R. Mov Disord. 2023 Apr;38(4):714-715. doi: 10.1002/mds.29353. PMID: 37061880

Effects of pair-housing pubertal and adult male and female mice on LPS-induced age-dependent immune responses: A potential role for the gut microbiota. Murray E, Butcher J, May Kearns M, Lamba S, Liang J, Stintzi A, Ismail N. Brain Behav Immun. 2023 May;110:297-309. doi: 10.1016/j.bbi.2023.03.009. Epub 2023 Mar 11.PMID: 36914014

Positive mood-related gut microbiota in a long-term closed environment: a multiomics study based on the "Lunar Palace 365" experiment.Hao Z, Meng C, Li L, Feng S, Zhu Y, Yang J, Han L, Sun L, Lv W, Figeys D, Liu H.Microbiome. 2023 Apr 24;11(1):88. doi: 10.1186/s40168-023-01506-0.PMID: 37095530

Molecularly Imprinted Nanobeacons Redirect Innate Immune Killing towards Triple Negative Breast Cancer. Guan P, Guo Z, Xu S, Lu H, Wang L, Gu Z, Liu Z. Angew Chem Int Ed Engl. 2023 Apr 17;62(17):e202301202. doi: 10.1002/anie.202301202. Epub 2023 Mar 10. PMID: 36814079

Granulosa cell-derived miR-379-5p regulates macrophage polarization in polycystic ovarian syndrome.Salehi R, Asare-Werehene M, Wyse BA, Abedini A, Pan B, Gutsol A, Jahangiri S, Szaraz P, Burns KD, Vanderhyden B, Li J, Burger D, Librach CL, Tsang BK.Front Immunol. 2023 Mar 24;14:1104550. doi: 10.3389/fimmu.2023.1104550. eCollection 2023.PMID: 37033997

Complexity in Hepatic Insulin Resistance - Unraveling the Role of Ubiquitin-Specific Protease 14 in Protein Homeostasis of Metabolic Transcription Factors. Morrow NM, Mulvihill EE. J Pharmacol Exp Ther. 2023 Apr;385(1):1-4. doi: 10.1124/jpet.122.001517. PMID: 36927510

Exercise training reduces circulating cytokines in male patients with coronary artery disease and type 2 diabetes: A pilot study.Garneau L, Terada T, Mistura M, Mulvihill EE, Reed JL, Aguer C.Physiol Rep. 2023 Mar;11(5):e15634. doi: 10.14814/phy2.15634.PMID: 36905198

Evaluating mitochondrial length, volume, and cristae ultrastructure in rare mouse adult stem cell populations.Triolo M, Wade S, Baker N, Khacho M. STAR Protoc. 2023 Feb 9;4(1):102107. doi: 10.1016/j.xpro.2023.102107. Online ahead of print. PMID: 36853728

Humoral Responses against BQ.1.1 Elicited after Breakthrough Infection and SARS-CoV-2 mRNA Vaccination. Tauzin A, Benlarbi M, Medjahed H, Grégoire Y, Perreault J, Gendron-Lepage G, Gokool L, Morrisseau C, Arlotto P, Tremblay C, Kaufmann DE, Martel-Laferrière V, Levade I, Côté M, De Serres G, Bazin R, Finzi A. Vaccines (Basel). 2023 Jan 21;11(2):242. doi: 10.3390/vaccines11020242. PMID: 36851122

Placental Mitochondrial Function and Dysfunction in Preeclampsia.Jahan F, Vasam G, Green AE, Bainbridge SA, Menzies KJ. Int J Mol Sci. 2023 Feb 20;24(4):4177. doi: 10.3390/ijms24044177. PMID: 36835587

Recent Developments in Islet Biology: A Review With Patient Perspectives. Basu L, Bhagat V, Ching MEA, Di Giandomenico A, Dostie S, Greenberg D, Greenberg M, Hahm J, Hilton NZ, Lamb K, Jentz EM, Larsen M, Locatelli CAA, Maloney M, MacGibbon C, Mersali F, Mulchandani CM, Najam A, Singh I, Weisz T, Wong J, Senior PA, Estall JL, Mulvihill EE, Screaton RA; for Diabetes Action Canada and the Canadian Islet Research and Training Network.Can J Diabetes. 2023 Mar;47(2):207-221. doi: 10.1016/j.jcjd.2022.11.003. Epub 2022 Nov 8.PMID: 36481263

Mycobacterium tuberculosis infection triggers epigenetic changes that are enriched in a type I IFN signature. Madden K, El Hamra R, Berton S, Felker J, Alvarez GG, Blais A, Sun J. Microlife. 2023 Feb 6;4:uqad006. doi: 10.1093/femsml/uqad006. eCollection 2023. PMID: 36820061

Early postnatal defects in neurogenesis in the 3xTg mouse model of Alzheimer's disease. Liu Y, Bilen M, McNicoll MM, Harris RA, Fong BC, Iqbal MA, Paul S, Mayne J, Walker K, Wang J, Figeys D, Slack RS. Cell Death Dis. 2023 Feb 18;14(2):138. doi: 10.1038/s41419-023-05650-1.

Multiomic spatial analysis reveals a distinct mucosa-associated virome. Yan A, Butcher J, Schramm L, Mack DR, Stintzi A. Gut Microbes. 2023 Jan-Dec;15(1):2177488. doi: 10.1080/19490976.2023.2177488. PMID: 36823020

Nuclear High Mobility Group A2 (HMGA2) Interactome Revealed by Biotin Proximity Labeling.Gaudreau-Lapierre A, Klonisch T, Nicolas H, Thanasupawat T, Trinkle-Mulcahy L, Hombach-Klonisch S.Int J Mol Sci. 2023 Feb 20;24(4):4246. doi: 10.3390/ijms24044246.PMID: 36835656

Prenatal low-dose methylmercury exposure causes premature neuronal differentiation and autism-like behaviors in a rodent model.Loan A, Leung JW, Cook DP, Ko C, Vanderhyden BC, Wang J, Chan HM.iScience. 2023 Jan 31;26(3):106093. doi: 10.1016/j.isci.2023.106093. eCollection 2023 Mar 17.PMID: 36843845 

Microbiota-directed biotherapeutics: considerations for quality and functional assessment.Emily Ef Fekete Daniel Figeys Xu Zhang

Proteomics characterization of mitochondrial‐derived vesicles under oxidative stress
Goutham Vasam, Rachel Nadeau, Virgilio J. J. Cadete, Mathieu Lavallée‐Adam, Keir J. Menzies, Yan Burelle FASEB J. 2021 Apr; 35(4): e21278. Published online 2021 Mar 26. doi: 10.1096/fj.202002151R PMCID: PMC8252493

Vtc5 Is Localized to the Vacuole Membrane by the Conserved AP-3 Complex to Regulate Polyphosphate Synthesis in Budding YeastAmanda Bentley-DeSousa, Michael DowneymBio. 2021 Sep-Oct; 12(5): e00994-21. Published online 2021 Sep 21. doi: 10.1128/mBio.00994-21
Correction in: mBio. 2021 Nov-Dec; 12(6): e02997-21.  PMCID: PMC8510523

Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cellsSabrina Robichaud, Garrett Fairman, Viyashini Vijithakumar, Esther Mak, David P. Cook, Alexander R. Pelletier, Sylvain Huard, Barbara C. Vanderhyden, Daniel Figeys, Mathieu Lavallée-Adam, Kristin Baetz, Mireille Ouimet
Autophagy. 2021; 17(11): 3671–3689. Published online 2021 Feb 26. doi: 10.1080/15548627.2021.1886839PMCID: PMC863232

Grx2 Regulates Skeletal Muscle Mitochondrial Structure and Autophagy
Ava Liaghati, Chantal A. Pileggi, Gaganvir Parmar, David A. Patten, Nina Hadzimustafic, Alexanne Cuillerier, Keir J. Menzies, Yan Burelle, Mary-Ellen Harper
Front Physiol. 2021; 12: 604210. Published online 2021 Mar 5. doi: 10.3389/fphys.2021.604210PMCID: PMC7982873

Naked mole-rat brown fat thermogenesis is diminished during hypoxia through a rapid decrease in UCP1
Hang Cheng, Rajaa Sebaa, Nikita Malholtra, Baptiste Lacoste, Ziyad El Hankouri, Alexia Kirby, Nigel C. Bennett, Barry van Jaarsveld, Daniel W. Hart, Glenn J. Tattersall, Mary-Ellen Harper, Matthew E. Pamenter
Nat Commun. 2021; 12: 6801. Published online 2021 Nov 23. doi: 10.1038/s41467-021-27170-2PMCID: PMC8610999

Applications of Extracellular Vesicles in Triple-Negative Breast Cancer
Frederic St-Denis-Bissonnette, Rachil Khoury, Karan Mediratta, Sara El-Sahli, Lisheng Wang, Jessie R. Lavoie  Cancers (Basel) 2022 Jan; 14(2): 451. Published online 2022 Jan 17. doi: 10.3390/cancers14020451 PMCID: PMC8773485

Ebola virus triggers receptor tyrosine kinase-dependent signaling to promote the delivery of viral particles to entry-conducive intracellular compartments
Corina M. Stewart, Alexandra Phan, Yuxia Bo, Nicholas D. LeBlond, Tyler K. T. Smith, Geneviève Laroche, Patrick M. Giguère, Morgan D. Fullerton, Martin Pelchat, Darwyn Kobasa, Marceline Côté
PLoS Pathog. 2021 Jan; 17(1): e1009275. Published online 2021 Jan 29. doi: 10.1371/journal.ppat.1009275PMCID: PMC7875390

Relative Ratios of Human Seasonal Coronavirus Antibodies Predict the Efficiency of Cross-Neutralization of SARS-CoV-2 Spike Binding to ACE2Yannick Galipeau, Vinayakumar Siragam, Geneviève Laroche, Erika Marion, Matthew Greig, Michaeline McGuinty, Ronald A Booth, Yves Durocher, Miroslava Cuperlovic-Culf, Steffany A.L. Bennett, Angela M. Crawley, Patrick M. Giguère, Curtis Cooper, Marc-André Langlois
EBioMedicine. 2021 Dec; 74: 103700. Published online 2021 Nov 30. doi: 10.1016/j.ebiom.2021.103700PMCID: PMC8629681

Retraction Note to: Differential regulation of wild-type and mutant alpha-synuclein binding to synaptic membranes by cytosolic factorsSabine Wislet-Gendebien, Naomi P. Visanji, Shawn N. Whitehead, Diana Marsilio, Weimin Hou, Daniel Figeys, Paul E. Fraser, Steffany A. L. Bennett, Anurag Tandon
BMC Neurosci. 2021; 22: 40. Published online 2021 Jun 3. doi: 10.1186/s12868-021-00644-1Retracts: BMC Neurosci. 2008; 9: 92.PMCID: PMC8173967

Identification of pannexin 1-regulated genes, interactome, and pathways in rhabdomyosarcoma and its tumor inhibitory interaction with AHNAKXiao Xiang, Stéphanie Langlois, Marie-Eve St-Pierre, Anna Blinder, Philippe Charron, Tyson E. Graber, Stephanie L. Fowler, Stephen D. Baird, Steffany A. L. Bennett, Tommy Alain, Kyle N. Cowan Oncogene. 2021; 40(10): 1868–1883. Published online 2021 Feb 9. doi: 10.1038/s41388-020-01623-2 PMCID: PMC7946643

Serine palmitoyltransferase assembles at ER–mitochondria contact sites
Mari J Aaltonen, Irina Alecu, Tim König, Steffany AL Bennett, Eric A Shoubridge
Life Sci Alliance. 2022 Feb; 5(2): e202101278. Published online 2021 Nov 16. doi: 10.26508/lsa.202101278 PMCID: PMC8605320

Metabolomics and computational analysis of the role of monoamine oxidase activity in delirium and SARS-COV-2 infectionMiroslava Cuperlovic-Culf, Emma L. Cunningham, Hossen Teimoorinia, Anuradha Surendra, Xiaobei Pan, Steffany A. L. Bennett, Mijin Jung, Bernadette McGuiness, Anthony Peter Passmore, David Beverland, Brian D. Green Sci Rep. 2021; 11: 10629. Published online 2021 May 20. doi: 10.1038/s41598-021-90243-1 PMCID: PMC8138024

Zebrafish Cancer Predisposition Models
Kim Kobar, Keon Collett, Sergey V. Prykhozhij, Jason N. Berman
Front Cell Dev Biol. 2021; 9: 660069. Published online 2021 Apr 27. doi: 10.3389/fcell.2021.660069 PMCID: PMC8112447

Six1 promotes skeletal muscle thyroid hormone response through regulation of the MCT10 transporter
John Girgis, Dabo Yang, Imane Chakroun, Yubing Liu, Alexandre Blais
Skelet Muscle. 2021; 11: 26. Published online 2021 Nov 19. doi: 10.1186/s13395-021-00281-6 PMCID:    PMC8607597

Chromatin and transcription factor profiling in rare stem cell populations using CUT&Tag
Yuefeng Li, Kiran Nakka, Thomas Olender, Philippe Gingras-Gelinas, Matthew Man-Kin Wong, Daniel C.L. Robinson, Hina Bandukwala, Carmen G. Palii, Odile Neyret, Marjorie Brand, Alexandre Blais, F. Jeffrey Dilworth
STAR Protoc. 2021 Sep 17; 2(3): 100751. Published online 2021 Aug 19. doi: 10.1016/j.xpro.2021.100751 PMCID:  PMC8384913

Muscle Enriched Lamin Interacting Protein (Mlip) Binds Chromatin and Is Required for Myoblast DifferentiationElmira Ahmady, Alexandre Blais, Patrick G. Burgon
Cells. 2021 Mar; 10(3): 615. Published online 2021 Mar 10. doi: 10.3390/cells10030615  PMCID: PMC7998221

Immunological and pathological outcomes of SARS-CoV-2 challenge following formalin-inactivated vaccine in ferrets and rhesus macaques
Kevin R. Bewley, Karen Gooch, Kelly M. Thomas, Stephanie Longet, Nathan Wiblin, Laura Hunter, Kin Chan, Phillip Brown, Rebecca A. Russell, Catherine Ho, Gillian Slack, Holly E. Humphries, Leonie Alden, Lauren Allen, Marilyn Aram, Natalie Baker, Emily Brunt, Rebecca Cobb, Susan Fotheringham, Debbie Harris, Chelsea Kennard, Stephanie Leung, Kathryn Ryan, Howard Tolley, Nadina Wand, Andrew White, Laura Sibley, Charlotte Sarfas, Geoff Pearson, Emma Rayner, Xiaochao Xue, Teresa Lambe, Sue Charlton, Sarah Gilbert, Quentin J. Sattentau, Fergus Gleeson, Yper Hall, Simon Funnell, Sally Sharpe, Francisco J. Salguero, Andrew Gorringe, Miles Carroll
Sci Adv. 2021 Sep; 7(37): eabg7996. Published online 2021 Sep 10. doi: 10.1126/sciadv.abg7996 PMCID: PMC8442907

Comparison of SARS-CoV-2 indirect and direct RT-qPCR detection methods
Joel D. Pearson, Daniel Trcka, Suying Lu, Sharon J. Hyduk, Mark Jen, Marie-Ming Aynaud, J. Javier Hernández, Philippos Peidis, Miriam Barrios-Rodiles, Kin Chan, Jim Woodgett, Tony Mazzulli, Liliana Attisano, Laurence Pelletier, Myron I. Cybulsky, Jeffrey L. Wrana, Rod Bremner
Virol J. 2021; 18: 99. Published online 2021 May 17. doi: 10.1186/s12985-021-01574-4 PMCID: PMC8127261

A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2
Marie-Ming Aynaud, J. Javier Hernandez, Seda Barutcu, Ulrich Braunschweig, Kin Chan, Joel D. Pearson, Daniel Trcka, Suzanna L. Prosser, Jaeyoun Kim, Miriam Barrios-Rodiles, Mark Jen, Siyuan Song, Jess Shen, Christine Bruce, Bryn Hazlett, Susan Poutanen, Liliana Attisano, Rod Bremner, Benjamin J. Blencowe, Tony Mazzulli, Hong Han, Laurence Pelletier, Jeffrey L. Wrana
Nat Commun. 2021; 12: 1405. Published online 2021 Mar 3. doi: 10.1038/s41467-021-21653-y PMCID: PMC7930244

Strong humoral immune responses against SARS-CoV-2 Spike after BNT162b2 mRNA vaccination with a 16-week interval between dosesAlexandra Tauzin, Shang Yu Gong, Guillaume Beaudoin-Bussières, Dani Vézina, Romain Gasser, Lauriane Nault, Lorie Marchitto, Mehdi Benlarbi, Debashree Chatterjee, Manon Nayrac, Annemarie Laumaea, Jérémie Prévost, Marianne Boutin, Gérémy Sannier, Alexandre Nicolas, Catherine Bourassa, Gabrielle Gendron-Lepage, Halima Medjahed, Guillaume Goyette, Yuxia Bo, Josée Perreault, Laurie Gokool, Chantal Morrisseau, Pascale Arlotto, Renée Bazin, Mathieu Dubé, Gaston De Serres, Nicholas Brousseau, Jonathan Richard, Roberta Rovito, Marceline Côté, Cécile Tremblay, Giulia C. Marchetti, Ralf Duerr, Valérie Martel-Laferrière, Daniel E. Kaufmann, Andrés Finzi
Cell Host Microbe. 2022 Jan 12; 30(1): 97–109.e5. Published online 2021 Dec 3. doi: 10.1016/j.chom.2021.12.004 PMCID: PMC8639412

Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of ConcernMadalina Elena Carter-Timofte, Rozanne Arulanandam, Naziia Kurmasheva, Kathy Fu, Geneviève Laroche, Zaid Taha, Demi van der Horst, Lena Cassin, Renée M. van der Sluis, Enrico Palermo, Daniele Di Carlo, David Jacobs, Glib Maznyi, Taha Azad, Ragunath Singaravelu, Fanghui Ren, Anne Louise Hansen, Manja Idorn, Christian K. Holm, Martin R. Jakobsen, Julien van Grevenynghe, John Hiscott, Søren R. Paludan, John C. Bell, Jean Seguin, Luc A. Sabourin, Marceline Côté, Jean-Simon Diallo, Tommy Alain, David Olagnier
ACS Infect Dis. 2021 Oct 18 : acsinfecdis.1c00278. Published online 2021 Oct 18. doi: 10.1021/acsinfecdis.1c00278 PMCID: PMC8547501

Contribution of single mutations to selected SARS-CoV-2 emerging variants spike antigenicity
Shang Yu Gong, Debashree Chatterjee, Jonathan Richard, Jérémie Prévost, Alexandra Tauzin, Romain Gasser, Yuxia Bo, Dani Vézina, Guillaume Goyette, Gabrielle Gendron-Lepage, Halima Medjahed, Michel Roger, Marceline Côté, Andrés Finzi
Virology. 2021 Nov; 563: 134–145. Published online 2021 Sep 11. doi: 10.1016/j.virol.2021.09.001 PMCID: PMC8433594

Antigenicity of the Mu (B.1.621) and A.2.5 SARS-CoV-2 Spikes
Debashree Chatterjee, Alexandra Tauzin, Annemarie Laumaea, Shang Yu Gong, Yuxia Bo, Aurélie Guilbault, Guillaume Goyette, Catherine Bourassa, Gabrielle Gendron-Lepage, Halima Medjahed, Jonathan Richard, Sandrine Moreira, Marceline Côté, Andrés Finzi
Viruses. 2022 Jan; 14(1): 144. Published online 2022 Jan 14. doi: 10.3390/v14010144 PMCID: PMC8780535

Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concernWenwei Li, Yaozong Chen, Jérémie Prévost, Irfan Ullah, Maolin Lu, Shang Yu Gong, Alexandra Tauzin, Romain Gasser, Dani Vézina, Sai Priya Anand, Guillaume Goyette, Debashree Chaterjee, Shilei Ding, William D. Tolbert, Michael W. Grunst, Yuxia Bo, Shijian Zhang, Jonathan Richard, Fei Zhou, Rick K. Huang, Lothar Esser, Allison Zeher, Marceline Côté, Priti Kumar, Joseph Sodroski, Di Xia, Pradeep D. Uchil, Marzena Pazgier, Andrés Finzi, Walther Mothes
Cell Rep. 2022 Jan 11; 38(2): 110210. Published online 2021 Dec 15. doi: 10.1016/j.celrep.2021.110210 PMCID: PMC8673750

Interferon-Induced HERC5 Inhibits Ebola Virus Particle Production and Is Antagonized by Ebola GlycoproteinErmela Paparisto, Nina R. Hunt, Daniel S. Labach, Macon D. Coleman, Eric J. Di Gravio, Mackenzie J. Dodge, Nicole J. Friesen, Marceline Côté, Andreas Müller, Thomas Hoenen, Stephen D. Barr
Cells. 2021 Sep; 10(9): 2399. Published online 2021 Sep 13. doi: 10.3390/cells10092399 PMCID: PMC8472148

Structural Basis and Mode of Action for Two Broadly Neutralizing Antibodies Against SARS-CoV-2 Emerging Variants of Concern
Wenwei Li, Yaozong Chen, Jérémie Prévost, Irfan Ullah, Maolin Lu, Shang Yu Gong, Alexandra Tauzin, Romain Gasser, Dani Vézina, Sai Priya Anand, Guillaume Goyette, Debashree Chaterjee, Shilei Ding, William D. Tolbert, Michael W. Grunst, Yuxia Bo, Shijian Zhang, Jonathan Richard, Fei Zhou, Rick K. Huang, Lothar Esser, Allison Zeher, Marceline Côté, Priti Kumar, Joseph Sodroski, Di Xia, Pradeep D. Uchil, Marzena Pazgier, Andrés Finzi, Walther Mothes
Version 1. bioRxiv. Preprint. 2021 Aug 3. doi: 10.1101/2021.08.02.454546 PMCID: PMC8351775

Identification of a High-Frequency Intrahost SARS-CoV-2 Spike Variant with Enhanced Cytopathic and Fusogenic EffectsLynda Rocheleau, Geneviève Laroche, Kathy Fu, Corina M. Stewart, Abdulhamid O. Mohamud, Marceline Côté, Patrick M. Giguère, Marc-André Langlois, Martin Pelchat
mBio. 2021 May-Jun; 12(3): e00788-21. Published online 2021 Jun 29. doi: 10.1128/mBio.00788-21 PMCID:  PMC8262852

Potential Differences in Cleavage of the S Protein and Type 1 Interferon Together Control Human Coronavirus Infection, Propagation, and Neuropathology within the Central Nervous SystemAlain Le Coupanec, Marc Desforges, Benedikt Kaufer, Philippe Dubeau, Marceline Côté, Pierre J. Talbot
J Virol. 2021 May; 95(10): e00140-21. Prepublished online 2021 Feb 24. Published online 2021 Apr 26. doi: 10.1128/JVI.00140-21 PMCID: PMC8139659

Dynamic sumoylation of promoter-bound general transcription factors facilitates transcription by RNA polymerase IIMohammad S. Baig, Yimo Dou, Benjamin G. Bergey, Russell Bahar, Justin M. Burgener, Marjan Moallem, James B. McNeil, Akhi Akhter, Giovanni L. Burke, Veroni S. Sri Theivakadadcham, Patricia Richard, Damien D’Amours, Emanuel Rosonina
PLoS Genet. 2021 Sep; 17(9): e1009828. Published online 2021 Sep 29. doi: 10.1371/journal.pgen.1009828 PMCID: PMC8505008  

Targeting Polyphosphate Kinases in the Fight against Pseudomonas aeruginosa
Kanchi Baijal, Michael Downey
mBio. 2021 Jul-Aug; 12(4): e01477-21. Published online 2021 Aug 3. doi: 10.1128/mBio.01477-21 PMCID:  PMC8406150

Erratum for Bentley-DeSousa and Downey, “Vtc5 Is Localized to the Vacuole Membrane by the Conserved AP-3 Complex To Regulate Polyphosphate Synthesis in Budding Yeast”Amanda Bentley-DeSousa, Michael Downey
mBio. 2021 Nov-Dec; 12(6): e02997-21. Published online 2021 Nov 2. doi: 10.1128/mBio.02997-21
Corrects: mBio. 2021 Sep-Oct; 12(5): e00994-21. PMCID: PMC8561339

Examining the Effects of an Anti-Salmonella Bacteriophage Preparation, BAFASAL^®, on Ex-Vivo Human Gut Microbiome Composition and Function Using a Multi-Omics ApproachJanice Mayne, Xu Zhang, James Butcher, Krystal Walker, Zhibin Ning, Ewelina Wójcik, Jarosław Dastych, Alain Stintzi, Daniel Figeys
Viruses. 2021 Sep; 13(9): 1734. Published online 2021 Aug 31. doi: 10.3390/v13091734 PMCID: PMC8473076

Propionic acid disrupts endocytosis, cell cycle, and cellular respiration in yeast
Emma W. Micalizzi, Ashkan Golshani, Myron L. Smith
BMC Res Notes. 2021; 14: 335. Published online 2021 Aug 28. doi: 10.1186/s13104-021-05752-z PMCID: PMC8403364

The conserved Tpk1 regulates non-homologous end joining double-strand break repair by phosphorylation of Nej1, a homolog of the human XLFMatthew Jessulat, Shahreen Amin, Mohsen Hooshyar, Ramy Malty, Mohamed Taha Moutaoufik, Mara Zilocchi, Zoe Istace, Sadhna Phanse, Hiroyuki Aoki, Katayoun Omidi, Daniel Burnside, Bahram Samanfar, Khaled A Aly, Ashkan Golshani, Mohan Babu
Nucleic Acids Res. 2021 Aug 20; 49(14): 8145–8160. Published online 2021 Jul 9. doi: 10.1093/nar/gkab585 PMCID: PMC8373142

Manganese-Induced Neurotoxicity through Impairment of Cross-Talk Pathways in Human Neuroblastoma Cell Line SH-SY5Y Differentiated with Retinoic AcidRaúl Bonne Hernández, Nadja C. de Souza-Pinto, Jos Kleinjans, Marcel van Herwijnen, Jolanda Piepers, Houman Moteshareie, Daniel Burnside, Ashkan Golshani
Toxics. 2021 Dec; 9(12): 348. Published online 2021 Dec 9. doi: 10.3390/toxics9120348 PMCID: PMC8704659

Dietary Cocoa Flavanols Enhance Mitochondrial Function in Skeletal Muscle and Modify Whole-Body Metabolism in Healthy MiceFrédéric Nicolas Daussin, Alexane Cuillerier, Julianne Touron, Samir Bensaid, Bruno Melo, Ali Al Rewashdy, Goutham Vasam, Keir J. Menzies, Mary-Ellen Harper, Elsa Heyman, Yan Burelle
Nutrients. 2021 Oct; 13(10): 3466. Published online 2021 Sep 29. doi: 10.3390/nu13103466 PMCID: PMC8538722

SMN Depleted Mice Offer a Robust and Rapid Onset Model of Nonalcoholic Fatty Liver Disease
Marc-Olivier Deguise, Chantal Pileggi, Yves De Repentigny, Ariane Beauvais, Alexandra Tierney, Lucia Chehade, Jean Michaud, Maica Llavero-Hurtado, Douglas Lamont, Abdelmadjid Atrih, Thomas M. Wishart, Thomas H. Gillingwater, Bernard L. Schneider, Mary-Ellen Harper, Simon H. Parson, Rashmi Kothary
Cell Mol Gastroenterol Hepatol. 2021; 12(1): 354–377.e3. Published online 2021 Feb 2. doi: 10.1016/j.jcmgh.2021.01.019 PMCID: PMC8257458

Nuclear HKII-P-p53 (Ser15) Interaction is a Prognostic Biomarker for Chemoresponsiveness and Glycolytic Regulation in Epithelial Ovarian CancerChae Young Han, David A. Patten, Se Ik Kim, Jung Jin Lim, David W. Chan, Michelle K. Y. Siu, Youngjin Han, Euridice Carmona, Robin J. Parks, Cheol Lee, Li-Jun Di, Zhen Lu, Karen K. L. Chan, Ja-Lok Ku, Elizabeth A. Macdonald, Barbara C. Vanderhyden, Anne-Marie Mes-Masson, Hextan Y. S. Ngan, Annie N. Y. Cheung, Yong Sang Song, Robert C. Bast, Jr., Mary-Ellen Harper, Benjamin K. Tsang
Cancers (Basel) 2021 Jul; 13(14): 3399. Published online 2021 Jul 7. doi: 10.3390/cancers13143399 PMCID: PMC8306240

Exercise training and diet-induced weight loss increase markers of hepatic bile acid (BA) synthesis and reduce serum total BA concentrations in obese womenKelly E. Mercer, Adrianna Maurer, Lindsay M. Pack, Kikumi Ono-Moore, Beverly J. Spray, Caitlin Campbell, Carol J. Chandler, Dustin Burnett, Elaine Souza, Gretchen Casazza, Nancy Keim, John Newman, Gary Hunter, Jose Fernadez, W. Timothy Garvey, Mary-Ellen Harper, Charles Hoppel, Sean H. Adams, John Thyfault
Am J Physiol Endocrinol Metab. 2021 May 1; 320(5): E864–E873. Published online 2021 Mar 1. doi: 10.1152/ajpendo.00644.2020 PMCID: PMC8238126

PIGNON: a protein–protein interaction-guided functional enrichment analysis for quantitative proteomicsRachel Nadeau, Anastasiia Byvsheva, Mathieu Lavallée-Adam
BMC Bioinformatics. 2021; 22: 302. Published online 2021 Jun 4. doi: 10.1186/s12859-021-04042-6 PMCID: PMC8178832

Nucleotide Analogues Bearing a C2′ or C3′-Stereogenic All-Carbon Quaternary Center as SARS-CoV-2 RdRp InhibitorsAmarender Manchoju, Renaud Zelli, Gang Wang, Carla Eymard, Adrian Oo, Mona Nemer, Michel Prévost, Baek Kim, Yvan Guindon
Molecules. 2022 Jan; 27(2): 564. Published online 2022 Jan 17. doi: 10.3390/molecules27020564 PMCID: PMC8781509

WACS: improving ChIP-seq peak calling by optimally weighting controls
Aseel Awdeh, Marcel Turcotte, Theodore J. Perkins
BMC Bioinformatics. 2021; 22: 69. Published online 2021 Feb 15. doi: 10.1186/s12859-020-03927-2 PMCID: PMC7885521

FHR-5 Serum Levels and CFHR5 Genetic Variations in Patients With Immune Complex-Mediated Membranoproliferative Glomerulonephritis and C3-Glomerulopathy
Nóra Garam, Marcell Cserhalmi, Zoltán Prohászka, Ágnes Szilágyi, Nóra Veszeli, Edina Szabó, Barbara Uzonyi, Attila Iliás, Christof Aigner, Alice Schmidt, Martina Gaggl, Gere Sunder-Plassmann, Dóra Bajcsi, Jürgen Brunner, Alexandra Dumfarth, Daniel Cejka, Stefan Flaschberger, Hana Flögelova, Ágnes Haris, Ágnes Hartmann, Andreas Heilos, Thomas Mueller, Krisztina Rusai, Klaus Arbeiter, Johannes Hofer, Dániel Jakab, Mária Sinkó, Erika Szigeti, Csaba Bereczki, Viktor Janko, Kata Kelen, György S. Reusz, Attila J. Szabó, Nóra Klenk, Krisztina Kóbor, Nika Kojc, Maarten Knechtelsdorfer, Mario Laganovic, Adrian Catalin Lungu, Anamarija Meglic, Rina Rus, Tanja Kersnik Levart, Ernesta Macioniene, Marius Miglinas, Anna Pawłowska, Tomasz Stompór, Ludmila Podracka, Michael Rudnicki, Gert Mayer, Romana Rysava, Jana Reiterova, Marijan Saraga, Tomáš Seeman, Jakub Zieg, Eva Sládková, Natasa Stajic, Tamás Szabó, Andrei Capitanescu, Simona Stancu, Miroslav Tisljar, Kresimir Galesic, András Tislér, Inga Vainumäe, Martin Windpessl, Tomas Zaoral, Galia Zlatanova, Mihály Józsi, Dorottya Csuka
Front Immunol. 2021; 12: 720183. Published online 2021 Sep 10. doi: 10.3389/fimmu.2021.720183 PMCID: PMC8461307

Antibody Response to mRNA Vaccines against SARS-CoV-2 with Chronic Kidney Disease, Hemodialysis, and after Kidney TransplantationLukas Buchwinkler, Claire Anne Solagna, Janosch Messner, Markus Pirklbauer, Michael Rudnicki, Gert Mayer, Julia Kerschbaum
J Clin Med. 2022 Jan; 11(1): 148. Published online 2021 Dec 28. doi: 10.3390/jcm11010148 PMCID: PMC8745313

Human Complement C4B Allotypes and Deficiencies in Selected Cases With Autoimmune Diseases
Danlei Zhou, Michael Rudnicki, Gilbert T. Chua, Simon K. Lawrance, Bi Zhou, Joanne L. Drew, Fatima Barbar-Smiley, Taylor K. Armstrong, Miranda E. Hilt, Daniel J. Birmingham, Werner Passler, Jeffrey J. Auletta, Sasigarn A. Bowden, Robert P. Hoffman, Yee Ling Wu, Wael N. Jarjour, Chi Chiu Mok, Stacy P. Ardoin, Yu Lung Lau, Chack Yung Yu
Front Immunol. 2021; 12: 739430. Published online 2021 Oct 26. doi: 10.3389/fimmu.2021.739430 PMCID: PMC8577214

Coregulation Analysis of Mechanistic Biomarkers in Autosomal Dominant Polycystic Kidney Disease
Johannes Leierer, Paul Perco, Benedikt Hofer, Susanne Eder, Alexander Dzien, Julia Kerschbaum, Michael Rudnicki, Gert Mayer
Int J Mol Sci. 2021 Jul; 22(13): 6885. Published online 2021 Jun 26. doi: 10.3390/ijms22136885 PMCID: PMC8269435

Acetylation of PAX7 controls muscle stem cell self-renewal and differentiation potential in mice
Marie-Claude Sincennes, Caroline E. Brun, Alexander Y. T. Lin, Tabitha Rosembert, David Datzkiw, John Saber, Hong Ming, Yoh-ichi Kawabe, Michael A. Rudnicki
Nat Commun. 2021; 12: 3253. Published online 2021 May 31. doi: 10.1038/s41467-021-23577-z PMCID: PMC8167170
STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancerStephanie P. Totten, Young Kyuen Im, Eduardo Cepeda Cañedo, Ouafa Najyb, Alice Nguyen, Steven Hébert, Ryuhjin Ahn, Kyle Lewis, Benjamin Lebeau, Rachel La Selva, Valérie Sabourin, Constanza Martínez, Paul Savage, Hellen Kuasne, Daina Avizonis, Nancy Santos Martínez, Catherine Chabot, Adriana Aguilar-Mahecha, Marie-Line Goulet, Matthew Dankner, Michael Witcher, Kevin Petrecca, Mark Basik, Michael Pollak, Ivan Topisirovic, Rongtuan Lin, Peter M. Siegel, Claudia L. Kleinman, Morag Park, Julie St-Pierre, Josie Ursini-Siegel
Nat Commun. 2021; 12: 3299. Published online 2021 Jun 3. doi: 10.1038/s41467-021-23396-2 PMCID: PMC8175605

Resistance to different anthracycline chemotherapeutics elicits distinct and actionable primary metabolic dependencies in breast cancerShawn McGuirk, Yannick Audet-Delage, Matthew G Annis, Yibo Xue, Mathieu Vernier, Kaiqiong Zhao, Catherine St-Louis, Lucía Minarrieta, David A Patten, Geneviève Morin, Celia MT Greenwood, Vincent Giguère, Sidong Huang, Peter M Siegel, Julie St-Pierre
eLife. 2021; 10: e65150. Published online 2021 Jun 28. doi: 10.7554/eLife.65150 PMCID: PMC8238502
Perturbations of cancer cell metabolism by the antidiabetic drug canagliflozin
David Papadopoli, Oro Uchenunu, Ranveer Palia, Nabila Chekkal, Laura Hulea, Ivan Topisirovic, Michael Pollak, Julie St-Pierre
Neoplasia. 2021 Apr; 23(4): 391–399. Published online 2021 Mar 27. doi: 10.1016/j.neo.2021.02.003 PMCID: PMC8027095
Glycomacropeptide for Management of Insulin Resistance and Liver Metabolic Perturbations
Mathilde Foisy Sauvé, Francis Feldman, Mireille Koudoufio, Nour-El-Houda Ould-Chikh, Lena Ahmarani, Alain Sane, Thierry N’Timbane, Ramy El-Jalbout, Nathalie Patey, Schohraya Spahis, Alain Stintzi, Edgard Delvin, Emile Levy
Biomedicines. 2021 Sep; 9(9): 1140. Published online 2021 Sep 2. doi: 10.3390/biomedicines9091140 PMCID: PMC8469639

Factors contributing to fidelity in a pilot trial of individualized resistant starches for pediatric inflammatory bowel disease: a fidelity study protocolGisell Castillo, David R. Mack, Manoj M. Lalu, Ruth Singleton, Dean A. Fergusson, Alain Stintzi, Megan Harrison, Justin Presseau Pilot Feasibility Stud. 2021; 7: 75. Published online 2021 Mar 19. doi: 10.1186/s40814-021-00815-1 PMCID: PMC7976693

Oligosaccharides and Microbiota in Human Milk Are Interrelated at 3 Months Postpartum in a Cohort of Women with a High Prevalence of Gestational Impaired Glucose ToleranceLauren LeMay-Nedjelski, Chloe Yonemitsu, Michelle R Asbury, James Butcher, Sylvia H Ley, Anthony J Hanley, Alex Kiss, Sharon Unger, Julia K Copeland, Pauline W Wang, Alain Stintzi, Lars Bode, Deborah L O'Connor
J Nutr. 2021 Nov; 151(11): 3431–3441. Published online 2021 Sep 11. doi: 10.1093/jn/nxab270 PMCID: PMC8562078

Reduced Infection Efficiency of Phage NCTC 12673 on Non-Motile Campylobacter jejuni Strains Is Related to Oxidative StressJessica C. Sacher, Muhammad Afzal Javed, Clay S. Crippen, James Butcher, Annika Flint, Alain Stintzi, Christine M. Szymanski
Viruses. 2021 Oct; 13(10): 1955. Published online 2021 Sep 29. doi: 10.3390/v13101955 PMCID: PMC8540345

Critical appraisal of the mechanisms of gastrointestinal and hepatobiliary infection by COVID-19
Emile Levy, Alain Stintzi, Albert Cohen, Yves Desjardins, André Marette, Schohraya Spahis
Am J Physiol Gastrointest Liver Physiol. 2021 Aug 1; 321(2): G99–G112. Published online 2021 May 19. doi: 10.1152/ajpgi.00106.2021 PMCID: PMC8289353

Resistant starch, microbiome, and precision modulation
Peter A. Dobranowski, Alain Stintzi
Gut Microbes. 2021; 13(1): 1926842. Published online 2021 Jul 18. doi: 10.1080/19490976.2021.1926842 PMCID: PMC8288039

Expansion microscopy-based imaging of nuclear structures in cultured cells
Antoine Gaudreau-Lapierre, Kirk Mulatz, Jean-Claude Béïque, Laura Trinkle-Mulcahy
STAR Protoc. 2021 Sep 17; 2(3): 100630. Published online 2021 Jun 26. doi: 10.1016/j.xpro.2021.100630 PMCID: PMC8243706

DNA Based Vaccine Expressing SARS-CoV-2 Spike-CD40L Fusion Protein Confers Protection Against Challenge in a Syrian Hamster ModelLevi A. Tamming, Diana Duque, Anh Tran, Wanyue Zhang, Annabelle Pfeifle, Emmanuel Laryea, Jianguo Wu, Sathya N. Thulasi Raman, Caroline Gravel, Marsha S. Russell, Anwar M. Hashem, Reem M. Alsulaiman, Rowa Y. Alhabbab, Jun Gao, David Safronetz, Jingxin Cao, Lisheng Wang, Wangxue Chen, Michael J. W. Johnston, Simon Sauve, Michael Rosu-Myles, Xuguang Li
Front Immunol. 2021; 12: 785349. Published online 2022 Jan 12. doi: 10.3389/fimmu.2021.785349 PMCID: PMC8789660

Serum Untargeted UHPLC-HRMS-Based Lipidomics to Discover the Potential Biomarker of Colorectal Advanced AdenomaYifan Zhu, Lisheng Wang, Yanying Nong, Yunxiao Liang, Zongsheng Huang, Pingchuan Zhu, Qisong Zhang
Cancer Manag Res. 2021; 13: 8865–8878. Published online 2021 Nov 26. doi: 10.2147/CMAR.S336322 PMCID: PMC8632617

Single Immunization of a Vaccine Vectored by a Novel Recombinant Vaccinia Virus Affords Effective Protection Against Respiratory Syncytial Virus Infection in Cotton RatsMarsha S. Russell, Sathya N. Thulasi Raman, Caroline Gravel, Wanyue Zhang, Annabelle Pfeifle, Wangxue Chen, Gary Van Domselaar, David Safronetz, Michael Johnston, Simon Sauve, Lisheng Wang, Michael Rosu-Myles, Jingxin Cao, Xuguang Li
Front Immunol. 2021; 12: 747866. Published online 2021 Sep 17. doi: 10.3389/fimmu.2021.747866 PMCID: PMC8484905

Carbon Material Based Electrochemical Immunosensor for Gastric Cancer Markers Detection
Zhuliang Zhang, Minsi Peng, Defeng Li, Jun Yao, Yingxue Li, Benhua Wu, Lisheng Wang, Zhenglei Xu
Front Chem. 2021; 9: 736271. Published online 2021 Aug 31. doi: 10.3389/fchem.2021.736271 PMCID: PMC8438142

Graphene-Assisted Electrochemical Sensor for Detection of Pancreatic Cancer Markers
Zhenglei Xu, Minsi Peng, Zhuliang Zhang, Haotian Zeng, Ruiyue Shi, Xiaoxin Ma, Lisheng Wang, Bihong Liao
Front Chem. 2021; 9: 733371. Published online 2021 Aug 19. doi: 10.3389/fchem.2021.733371 PMCID: PMC8416602

Hollow-fiber bioreactor production of extracellular vesicles from human bone marrow mesenchymal stromal cells yields nanovesicles that mirrors the immuno-modulatory antigenic signature of the producer cellJonathan Gobin, Gauri Muradia, Jelica Mehic, Carole Westwood, Lauren Couvrette, Andrew Stalker, Stewart Bigelow, Christian C. Luebbert, Frédéric St-Denis Bissonnette, Michael J. W. Johnston, Simon Sauvé, Roger Y. Tam, Lisheng Wang, Michael Rosu-Myles, Jessie R. Lavoie
Stem Cell Res Ther. 2021; 12: 127. Published online 2021 Feb 12. doi: 10.1186/s13287-021-02190-3 PMCID: PMC7880218
Long noncoding RNA KIF9-AS1 promotes cell apoptosis by targeting the microRNA-148a-3p/suppressor of cytokine signaling axis in inflammatory bowel diseaseJun Yao, Ruoyu Gao, Minghan Luo, Defeng Li, Liliangzi Guo, Zichao Yu, Feng Xiong, Cheng Wei, Benhua Wu, Zhenglei Xu, Dingguo Zhang, Jianyao Wang, Lisheng Wang
Eur J Gastroenterol Hepatol. 2021 Dec; 33(Suppl 1): e922–e932. Published online 2021 Nov 8. doi: 10.1097/MEG.0000000000002309 PMCID: PMC8734634

Identification of Active Ingredients of Huangqi Guizhi Wuwu Decoction for Promoting Nerve Function Recovery After Ischemic Stroke Using HT22 Live-Cell-Based Affinity Chromatography Combined with HPLC-MS/MSYingying He, Haozhen Zheng, Lanying Zhong, Nijun Zhong, Guiqing Wen, Lisheng Wang, Ying Zhang
Drug Des Devel Ther. 2021; 15: 5165–5178. Published online 2021 Dec 30. doi: 10.2147/DDDT.S333418 PMCID: PMC8722572
COVID-MTL: Multitask learning with Shift3D and random-weighted loss for COVID-19 diagnosis and severity assessmentGuoqing Bao, Huai Chen, Tongliang Liu, Guanzhong Gong, Yong Yin, Lisheng Wang, Xiuying Wang
Pattern Recognit. 2022 Apr; 124: 108499. Published online 2021 Dec 12. doi: 10.1016/j.patcog.2021.108499 PMCID: PMC8666107
Synthetic vaccine affords full protection to mice against lethal challenge of influenza B virus of both genetic lineagesCaroline Gravel, Abenaya Muralidharan, Amparo Duran, Adrian Zetner, Annabelle Pfeifle, Wanyue Zhang, Anwar Hashem, Levi Tamming, Aaron Farnsworth, Hugues Loemba, Wangxue Chen, Florian Krammer, David Safronetz, Jingxin Cao, Lisheng Wang, Simon Sauve, Michael Rosu-Myles, Gary Van Domselaar, Xuguang Li
iScience. 2021 Nov 19; 24(11): 103328. Published online 2021 Oct 21. doi: 10.1016/j.isci.2021.103328 PMCID: PMC8586812

Quantitative Prediction of Microsatellite Instability in Colorectal Cancer With Preoperative PET/CT-Based RadiomicsJiaru Li, Ziyi Yang, Bowen Xin, Yichao Hao, Lisheng Wang, Shaoli Song, Junyan Xu, Xiuying Wang
Front Oncol. 2021; 11: 702055. Published online 2021 Jul 22. doi: 10.3389/fonc.2021.702055 PMCID: PMC8339969

Correction to: Automatic identification of myopic maculopathy related imaging features in optic disc region via machine learning methodsYuchen Du, Qiuying Chen, Ying Fan, Jianfeng Zhu, Jiangnan He, Haidong Zou, Dazhen Sun, Bowen Xin, David Feng, Michael Fulham, Xiuying Wang, Lisheng Wang, Xun Xu
J Transl Med. 2021; 19: 203. Published online 2021 May 11. doi: 10.1186/s12967-021-02874-7  Corrects: J Transl Med. 2021; 19: 167. PMCID: PMC8114694

Expression of Nutrient Transporters on NK Cells During Murine Cytomegalovirus Infection Is MyD88-DependentAbrar Ul Haq Khan, Saeedah Musaed Almutairi, Alaa Kassim Ali, Rosalba Salcedo, C. Andrew Stewart, Lisheng Wang, Seung-Hwan Lee Front Immunol. 2021; 12: 654225. Published online 2021 May 3. doi: 10.3389/fimmu.2021.654225 PMCID: PMC8177011

Imaging Features by Machine Learning for Quantification of Optic Disc Changes and Impact on Choroidal Thickness in Young Myopic PatientsDandan Sun, Yuchen Du, Qiuying Chen, Luyao Ye, Huai Chen, Menghan Li, Jiangnan He, Jianfeng Zhu, Lisheng Wang, Ying Fan, Xun Xu
Front Med (Lausanne) 2021; 8: 657566. Published online 2021 Apr 29. doi: 10.3389/fmed.2021.657566 PMCID: PMC8116583

Post-Alignment Adjustment and Its Automation
Xuhua Xia
Genes (Basel) 2021 Nov; 12(11): 1809. Published online 2021 Nov 18. doi: 10.3390/genes12111809 PMCID: PMC8623120

Detailed Dissection and Critical Evaluation of the Pfizer/BioNTech and Moderna mRNA Vaccines
Xuhua Xia
Vaccines (Basel) 2021 Jul; 9(7): 734. Published online 2021 Jul 3. doi: 10.3390/vaccines9070734 PMCID: PMC8310186

Applications of Protein Secondary Structure Algorithms in SARS-CoV-2 Research
Alibek Kruglikov, Mohan Rakesh, Yulong Wei, Xuhua Xia
J Proteome Res. 2021 Mar 5; 20(3): 1457–1463. Published online 2021 Feb 22. doi: 10.1021/acs.jproteome.0c00734 PMCID: PMC7927282
Author Correction: Predicting mammalian species at risk of being infected by SARS-CoV-2 from an ACE2 perspectiveYulong Wei, Parisa Aris, Heba Farookhi, Xuhua Xia
Sci Rep. 2021; 11: 22016. Published online 2021 Nov 4. doi: 10.1038/s41598-021-01576-w
Corrects: Sci Rep. 2021; 11: 1702. PMCID: PMC8567729

Dating the Common Ancestor from an NCBI Tree of 83688 High-Quality and Full-Length SARS-CoV-2 GenomesXuhua Xia
Viruses. 2021 Sep; 13(9): 1790. Published online 2021 Sep 8. doi: 10.3390/v13091790 PMCID: PMC8472983

Does Saccharomyces cerevisiae Require Specific Post-Translational Silencing against Leaky Translation of Hac1up?
Ali Tehfe, Talia Roseshter, Yulong Wei, Xuhua Xia
Microorganisms. 2021 Mar; 9(3): 620. Published online 2021 Mar 17. doi: 10.3390/microorganisms9030620 PMCID: PMC8002603