How the TEM Core Facility can support your research
- TEM capable of imaging any tissue (properly embedded and ultrathin-sectioned)
- Spatial resolution down to few nanometers (e.g. magnifications ranging from 1,000x to ~100,000x at 60 kv)
- In-house expertise available to help you plan and execute your imaging goals
- Protocols in place for tissue fixation and immune-EM labeling
- Strategic Location on the second floor of Roger Guindon Hall, between the General Campus and CHEO
- Time slots readily available during the day
- Competitive academic rates at 50$/hour for instrument usage and image acquisition time (80$/hour for external users).
Applications (some examples)
- Cellular ultrastructure
- Organelle remodeling
- Synaptic density, architecture
- Membrane biology, endoplasmic reticulum, nuclear pores
- Mitochondrial fusion, fission
- Autophagosome analysis
- Blood-brain barrier integrity
- Vesicular trafficking
- Etc.
