Dr. Deborah Siegal

Dr. Deborah Siegal
Dr. Deborah Siegal
Associate Professor
Hematologist (Thrombosis), The Ottawa Hospital
Associate Scientist, Clinical Epidemiology Program, Ottawa Hospital Research Institute



Dr. Deborah Siegal is a hematologist (thrombosis medicine) and clinician-scientist, Associate Professor in the Department of Medicine and School of Epidemiology and Public Health at the University of Ottawa, and Associate Scientist at the Ottawa Hospital Research Institute. She holds a Tier 2 Canada Research Chair in Anticoagulant Management of Cardiovascular Disease.  

Dr. Siegal received a B.Sc. in Physiology (McGill University, 1998), M.Sc. in Pharmacology (University of Toronto, 2001), M.D. (Queen’s University, 2009), and M.Sc. in Health Research Methodology (McMaster University, 2017). With an h-index of 36, Dr. Siegal has published over 120 peer-reviewed articles including high-impact first and last author publications in journals such as New England Journal of Medicine, Annals of Internal Medicine, Circulation, Journal of the American College of Cardiology, Journal of Thrombosis and Haemostasis, European Heart Journal and Blood.

Dr. Siegal’s research program aims to improve the outcomes of patients with cardiovascular disease by optimizing the use of antithrombotic therapies in the following areas: 1) Management of anticoagulant-related bleeding complications; 2) Prevention of anticoagulant-related gastrointestinal bleeding; 3) Perioperative management and outcomes of anticoagulated patients requiring urgent (unplanned) surgery; 4) Epidemiology, antithrombotic management and outcomes of patients with cancer who experience ischemic stroke; and 5) Reducing iatrogenic blood loss and transfusion in critically ill patients. Her research projects involve a number of methodologies including evidence synthesis, pilot studies, individual patient and cluster randomized trials, observational studies and mixed-methods studies.

Dr. Siegal’s research has been funded by peer-reviewed grants from Canadian Institutes of Health Research (CIHR), American Society of Hematology (ASH), Ontario AHSC AFP Innovation Fund (HAHSO and TOHAMO), Ottawa Hospital Research Institute, Heart and Stroke Foundation of Canada/CanVECTOR, Canadian Stroke Consortium/Brain Canada, and Hamilton Health Sciences.