Metal hydrides promote a wide-range of organic transformations that include both C-C bond making and C-C bond breaking processes. This lecture will highlight the development of Rh and Co-catalysts for use in enantioselective hydrofunctionalizations (e.g., hydroacylation, hydroamination, and hydrothiolation). In addition, a unique transfer hydroformylation will be described that allows conversion of aldehydes/alcohols to olefins. The presentation emphasizes mechanistic studies that showcase the role of counter-ions for controlling selectivities. Lastly, we disclose applications of these catalysts for transforming feedstocks into more complex building blocks and natural products.

Vy Dong

Prof. Vy Dong

Department of Chemistry, University of California

Prof. Vy Dong was born in Big Spring, Texas and spent early childhood in west Texas before moving with family to Anaheim, California. She graduated magna cum laude from UC Irvine where she majored in chemistry and completed an honor's project with Larry Overman on the tethered Bignelli condensation. After graduation, she joined David MacMillan's group at UC Berkeley as one of his first students. She then moved with his group to Caltech to complete her doctoral studies. Her Ph.D. thesis featured variants of the zwitterionic-Claisen rearrangement and a total synthesis of erythronolide B. As an NIH postdoctoral fellow, Vy pursued training in organometallic and supramolecular chemistry with Robert Bergman and Kenneth Raymond at Berkeley. She began her independent academic career at the University of Toronto, where she was promoted with tenure and named the Adrian Brook Professor. After six years in Canada, Vy returned to the United States to assume a professorship at her alma mater, UC Irvine. Professor Dong's research team is interested in new reaction methods, enantioselective catalysis, and natural product synthesis. Her team has been recognized by the ACS EJ Corey Award, ACS Cope Scholar Award, and Alfred P. Sloan Fellowship. Professor Dong teaches introductory organic chemistry and advanced synthesis courses. She also serves as the associate editor for the Royal Society of Chemistry's flagship journal, Chemical Science.

Vy Dong group website

Date and time
Apr 27, 2022
Organized by
Departmental seminars

Everyone is welcome.

Contact info

Prof. Eva Hemmer

Associate Professor, Department of Chemistry and Biomolecular Sciences

Phone: +1-613-562-5800 ext. 1987

Website: www.hemmerlab.com