Through his research programs, Dr. Bryce develops and applies solid-state NMR spectroscopic and quantum chemical methods for the study of nuclei in unique bonding environments in diverse solid compounds, cocrystals, and materials. One of the goals is to establish tools for providing new insights into supramolecular materials and related systems. Non-covalent halogen bonds, pnictogen bonds, chalcogen bonds, and tetrel bonds are a current focus. NMR crystallography, crystal engineering, and mechanochemistry are also particular areas of interest and application. In addition to providing fundamentally new chemical knowledge on structure and bonding in such systems, one of the aims is to establish solid-state NMR as more of a predictive tool in the characterization of inorganic and bioinorganic molecules.
Professor Bryce is accepting graduate students.
Selected publications
- A. Nari, M. Rahman, P. M. J. Szell, V. Semeniuchenko, and D. L. Bryce. Halogen Bond Strength in Solids Quantified via Zeeman-Perturbed Nuclear Quadrupole Resonance Spectroscopy. J. Am. Chem. Soc. 147, 9528-9543 (2025).
- G. Cosby, T. Iftimie, A. Nari, and D. L. Bryce. Chalcogen-Bonded Cocrystals and Salt Cocrystals via Automated Resonant Acoustic Mixing with a Button Operative Bot. RSC Mechanochemistry, 2, 201-208 (2025).
- T. Nag, V. V. Terskikh, and D. L. Bryce. Experimental Evidence for Non-Fermi-Contact J Coupling Across Chalcogen Bonds in Ionic Salt Cocrystal Polymorphs. Angew. Chem. Int. Ed., 63, e202402441 (2024).
- S. S. Gunaga and D. L. Bryce. Modulation of Rotational Dynamics in Halogen-Bonded Cocrystalline Solids. J. Am. Chem. Soc., 145, 19005-19017 (2023).
- P. M. J. Szell, S. Zablotny, and D. L. Bryce. Halogen Bonding as a Supramolecular Dynamics Catalyst. Nature Commun., 10, article number 916, (2019).
- Y. T. A. Wong, J. Landmann, M. Finze, and D. L. Bryce. Dynamic Disorder and Electronic Structures of Electron-Precise Dianionic Diboranes: Insights from Solid-State Multinuclear Magnetic Resonance Spectroscopy. J. Am. Chem. Soc., 139, 8200-8211 (2017). PDF.
- F. A. Perras and D. L. Bryce. Symmetry-Amplified J Splittings for Quadrupolar Spin Pairs: A Solid-State NMR Probe of Homoatomic Covalent Bonds. J. Am. Chem. Soc., 135, 12596 (2013).
- M. J. Plevin, D. L. Bryce, and J. Boisbouvier. Direct Detection of CH/pi Interactions in Proteins. Nature Chem., 2, 466-471 (2010).