Howard Alper
Howard Alper
Distinguished University Professor

DRO 402
(613) 562-5800 ext. 5189

Department of Chemistry and Biomolecular Sciences


Dr. Howard Alper conducts basic research for the synthesis of compounds of value to the pharmaceutical, petrochemical, and commodity chemical industries. His research group also investigates hydroformylation, ring-expansion carbonylation reactions, as well as stereospecific and highly enantioselective cycloaddition reactions of heterocumulenes. He also explores the activity and recyclability of dendrimer-metal complexes as catalysts, including biomimetic based systems. Recyclable transition metal catalysis using ionic liquids is also pursued by his research group.

  • Sha, F.; Alper, H. Ligand and Additive-Controlled Pd-Catalyzed Aminocarbonylation of Alkynes with Aminophenols: Highly Chemo- and Regioselective Synthesis of alpha, beta-Unsaturated Amides. ACS Catalysis 2019, 7, 2220.
  • Xu, T.; Sha, F.; Alper, H. Highly Ligand-Controlled Regioselective Pd-Catalyzed Aminocarbonylation of Styrenes with Aminophenols. J. Am. Chem. Soc. 2016, 138, 6629.
  • Xuan, J.; Zeng, Z.J.; Feng, Q.H.; Deng, J.R.; Chen, L.Q.; Xiao, W.J.; Alper, H. Redox-Neutral alpha-Allylation of Amines by Combining Palladium Catalysis and Visible-Light Photoredox Catalysis. Angew. Chem. Int. Ed. 2015, 54, 1625.
  • Xu, T.; Alper, H. Pd-Catalyzed Chemoselective Carbonylation of Aminophenols With Iodoarenes: Alkoxycarbonylation vs. Aminocarbonylation. J. Am. Chem. Soc. 2014, 136, 16974.

Research interests

  • Organic and Biological Chemistry
  • Inorganic and Organometallic Chemistry
  • Catalysis
  • Asymmetric synthesis
  • Dendrimers
  • Cyclization