All information on employment opportunities for faculty, students, postdoctoral fellows, and research personnel, can be found here.
New Tenure-Track position with CMM available now. For more information please click here!
New and renewal of appointments: Cross-appointments and Adjunct memberships
You wish to apply or renew a Cross-appointment or an Adjunct membership with the Department of Cellular and Molecular Medicine? Please do not hesitate to communicate with Christina Sardella for further information.
Potential Start Date: August 1, 2023
Full-Time Junior Technician position to perform animal testing within the Behavioral and Physiology Core in Roger Guindon Hall at the University of Ottawa.
The Behavior and Physiology Core is a state-of-the-art facility equipped to serve the research community at the University of Ottawa, its affiliated Research Institutes, and external users through contracts. The Core provides a time-efficient and cost-effective service for the design, execution, analysis, interpretation, and presentation of data resulting from use of the Core's facilities.
The equipment enables a full battery of assays relevant to learning and memory, social behavior, sensory gating, motor function, and mood disorders. In addition, the core offers equipment to perform in vivo optogenetics, small animal telemetry, and non-invasive determinations of body composition and metabolic parameters.
The primary responsibility of this position will be to perform behavioral testing in mice and rats using standardized protocols. This person will also work with other core staff to set up testing, maintain equipment, and analyze data obtained within the core. Applicants should be able to work independently, be detail-focused, and be comfortable interacting with coworkers and a wide variety of Core users.
Minimum of Undergraduate Degree in a related field, Technical College Degree in a related field, and/or minimum of 1 year experience in research or working as an animal technician. Preferable either M.Sc. or veterinary care certificate required.
Practical experience with mice (prefer mice and rats)
Experience using computer systems and software, particularly Microsoft Office software Excellent written and oral communication skills (prefer bilingual in French and English, but English is essential)
Support is in accordance with University of Ottawa standards. This is a non-unionized contractual research staff position (35hr/week, with flexible hours including some weekend hours) at the level of a Junior Technician NR1.
Qualified candidates should send a short letter of introduction describing their previous expertise and reasons for applying for this job, CV, and the names of three references to: Behavior and Physiology Core Advisory Committee, in care of Christina Sardella [email protected]
A postdoctoral fellow position is available in the laboratory of Dr. Nongnuj Tanphaichitr, Ottawa Hospital Research Institute (OHRI), to carry out a new research project. In this study, the candidate will develop dosage formulation (delivery system) of antimicrobial peptides (AMPs) to be administered intravaginally. We will focus on the cathelicidin AMP, LL-37, and its derived peptide, 17BIPHE2, which possess both spermicidal and microbicidal activity (Kiattiburut et al., Human Reprod 2018, 33:2175-2183). As Multipurpose Prevention Technology (MPT) agents, these AMPs will provide women with empowerment to protect themselves against unwanted pregnancies and sexually transmitted infections. This study is funded by Canadian Institutes of Health Research (CIHR) and is being carried out in both mouse (in vitro and in vivo) and human (in vitro and ex vivo) systems.
Candidates must have a Ph.D. in biochemistry, cell biology/physiology or related biomedical fields with ability to communicate well at both oral and written levels. Knowledge and lab experience in the female reproductive physiology, sperm biology, and hydrogel and/or nanoparticles-based drug delivery to the vagina will give priorities in the recruitment. Self-motivation to progress in his/her career as an independent investigator will also be favorably considered.
Salary and benefits will be commensurate with the candidate’s experience, following the guideline of OHRI. The term of employment can be up to 4 years. OHRI is one of the foremost Canadian hospital-based research institutes with investigators performing research focusing on answering important health questions and translating their findings into benefits for mankind. A sizable group of researchers in the field of reproductive biology are members of OHRI and also other academic institutes in Ottawa.
Please send your CV with description of research experience and names of three references to [email protected]
Postdoctoral positions are available in the laboratory of Dr. Xiaohui Zha at Ottawa Hospital Research Institute/University of Ottawa, Canada
The project is to study the mechanisms by which cholesterol regulates macrophage inflammation, a key event in atherosclerosis. Cholesterol, a major component of the plasma membrane in mammalian cells, predominantly regulates membrane physical properties. Most likely through its modulation of cellular membranes, cholesterol impacts numerous signal transduction pathways and cellular processes. Particularly, cholesterol levels in macrophages determine the nature of the inflammation response, for example, pro-inflammatory response (M1), anti-inflammatory (M2) or anything in between. The mechanism is largely unknown. In recent years, it is increasingly apparent that macrophages can respond to environmental cues to establish an epigenetically “poised” state. This allows macrophages to rapidly launch a large-scale gene expression program upon stimulation (i.e. LPS). The project will use biochemistry and genomic techniques, such as RNA-seq and ChIP-seq, to understand how cholesterol establishes epigenetically “poised” states in the genome of the macrophages to regulate gene expression for inflammatory responses.
Candidates should be a fresh PhD (less than two years since graduation) in physical science or biological science with good publication record. Knowledge/experience in genomic system biology is a plus, but not necessary. If interested, please send curriculum vitae and brief statement of research interest to [email protected]
Xiaohui Zha, Senior Scientist
Chronic Disease Program
Ottawa Hospital Research Institute
501 Smyth Road, Ottawa, ON K1H 8L6