Career Opportunities

Female student doing research experiment in lab — Faculty of Medicine

Cellular and Molecular Medicine - CMM

Career Opportunities

All information on employment opportunities for faculty, students, postdoctoral fellows, and research personnel, can be found here.

New Tenure-Track position with CMM available now. For more information please click here!

New and renewal of appointments: Cross-appointments and Adjunct memberships

You wish to apply or renew a Cross-appointment or an Adjunct membership with the Department of Cellular and Molecular Medicine? Please do not hesitate to communicate with Gina Campbell at [email protected] for further information.

Description:	A postdoctoral fellow position is available in the laboratory of Dr. Nongnuj Tanphaichitr, Ottawa Hospital Research Institute (OHRI), to carry out a new research project. In this study, the candidate will develop dosage formulation (delivery system) of antimicrobial peptides (AMPs) to be administered intravaginally. We will focus on the cathelicidin AMP, LL-37, and its derived peptide, 17BIPHE2, which possess both spermicidal and microbicidal activity (Kiattiburut et al., Human Reprod 2018, 33:2175-2183). As Multipurpose Prevention Technology (MPT) agents, these AMPs will provide women with empowerment to protect themselves against unwanted pregnancies and sexually transmitted infections. This study is funded by Canadian Institutes of Health Research (CIHR) and is being carried out in both mouse (in vitro and in vivo) and human (in vitro and ex vivo) systems.
Requirements:	Candidates must have a Ph.D. in biochemistry, cell biology/physiology or related biomedical fields with ability to communicate well at both oral and written levels. Knowledge and lab experience in the female reproductive physiology, sperm biology, and hydrogel and/or nanoparticles-based drug delivery to the vagina will give priorities in the recruitment. Self-motivation to progress in his/her career as an independent investigator will also be favorably considered.
Salary:	Salary and benefits will be commensurate with the candidate’s experience, following the guideline of OHRI. The term of employment can be up to 4 years. OHRI is one of the foremost Canadian hospital-based research institutes with investigators performing research focusing on answering important health questions and translating their findings into benefits for mankind. A sizable group of researchers in the field of reproductive biology are members of OHRI and also other academic institutes in Ottawa.
To apply:	Please send your CV with description of research experience and names of three references to [email protected]

General information:	Postdoctoral positions are available in the laboratory of Dr. Xiaohui Zha at Ottawa Hospital Research Institute/University of Ottawa, Canada
Project description:	The project is to study the mechanisms by which cholesterol regulates macrophage inflammation, a key event in atherosclerosis. Cholesterol, a major component of the plasma membrane in mammalian cells, predominantly regulates membrane physical properties. Most likely through its modulation of cellular membranes, cholesterol impacts numerous signal transduction pathways and cellular processes. Particularly, cholesterol levels in macrophages determine the nature of the inflammation response, for example, pro-inflammatory response (M1), anti-inflammatory (M2) or anything in between. The mechanism is largely unknown. In recent years, it is increasingly apparent that macrophages can respond to environmental cues to establish an epigenetically “poised” state. This allows macrophages to rapidly launch a large-scale gene expression program upon stimulation (i.e. LPS). The project will use biochemistry and genomic techniques, such as RNA-seq and ChIP-seq, to understand how cholesterol establishes epigenetically “poised” states in the genome of the macrophages to regulate gene expression for inflammatory responses.
Basic requirements:	Candidates should be a fresh PhD (less than two years since graduation) in physical science or biological science with good publication record. Knowledge/experience in genomic system biology is a plus, but not necessary. If interested, please send curriculum vitae and brief statement of research interest to [email protected]
Contact info:	Xiaohui Zha, Senior Scientist Chronic Disease Program Ottawa Hospital Research Institute 501 Smyth Road, Ottawa, ON K1H 8L6

Career opportunities with the Faculty of Medicine

New Tenure-Track position with CMM available now. For more information please click here!

New and renewal of appointments: Cross-appointments and Adjunct memberships

Research Technician position available in the Trinkle Lab arrow_drop_down

Postdoctoral position in Tanphaichitr lab arrow_drop_down

Postdoctoral position arrow_drop_down