The facility is equipped with a variety of reaction, sampling, and analytical tools from value-added equipment distributors as well as from the OEMs.

Overview

Every process comes with a unique set of requirements and complexities. In the realm of flow chemistry and continuous manufacturing, one shoe size hardly fits all. That's why the facility collaborates with the OEMs and develops custom solutions in addition to purchasing the latest and the greatest that the commercial market has to offer. The following is an abbreviated list of custom hardware tools that we make available for your research. We ensure that the technology for your research objectives is built from the fundamental principle of fluid management and fluid dynamics in order for you to have the maximum flexibility in the functioning of the device.

Key areas of expertise

  • Continuous Manufacturing (CM)
  • Continuous Process Validation (CPV)
  • Process Analytical Technology (PAT)
  • Inline, Online, At-line, and Offline Sampling
  • Closed Loop Feedback
  • Automation
  • Intelligent Reactor Technology
  • Process Intensification
  • Process Development and Technology Transfer

      Lead specialist, lab support

      The Flow Research Facility at the University of Ottawa is managed by Dr. Debasis Mallik. Dr. Mallik has experience in flow chemistry and analysis for over 10 years. Before joining the University of Ottawa, he managed a team of chemists, analysts, engineers, and programmers towards building a PAT-enabled autonomous continuous manufacturing platform at York University. He is co-inventors of three key technologies in the area of fluid diverting and analysis. He has co-authored a number of publications, reviews, and book chapters on continuous manufacturing and analysis.

      Dr. Mallik’s areas of expertise

      • Process Intensification and Analysis
      • Documentation, Publication, and Patenting
      • Designing and Prototyping
      • Project Management
      • Training and Guidance
        Mallik Debasis

        Technologies available through the facility

        Solid handling valve

        Slurry-handling LSVs

        The ability to monitor a flowed reaction irrespective of how hazardous the sampling technique empowers process chemists to make critical decisions on the process.
        BPR-less pressurized flow reactor technology

        BPR-less pressurized flow reactor technology

        Unlike batch chemistry, reagents have a short tenure at the energized zone in flow format. More importantly, reagents must exit the reactor through the outlet of the reactor tube at a steady flow-rate.
        Multi-function LSVs

        Multi-function LSVs

        It's quite common to have an array of valves in a process workflow in order to orchestrate complex fluid movements through a reactor network.

        Over 50 years of collective experience

        The facility's researchers are empowered with over 50+ years of aggregate experience in the science and engineering of continuous manufacturing and process analytical technology. The members of the facility not only have extensive operational knowledge of commercially available flow systems, but also work with the OEMs of commercial flow systems toward developing the next-gen systems and continuous manufacturing processes. This sets the facility in a unique position to not only develop new 'flow' methods to replace traditional batch manufacturing, but also derive technological solutions beyond what 'off-the-shelf' units can deliver.

        Flow Manufacturing and Technology Development

        Contact us

        Flow Chemistry Core Facility

        Debasis Mallik
        Lead Specialist and Flow Chemistry Manager
        Telephone: (613) 562-5800, ext. 6353
        [email protected]