The Biological John L. Holmes Mass Spectrometry Facility at the University of Ottawa provides support for high quality research activities and enhances the educational experience of students.


Dr. Zoran Minic

Dr. Zoran MINIC

Division Facility Manager, Biological Mass Spectrometrist

Zoran Minic received his M.Sc. in Integrative Systems Biology and Pharmacology in 1995 and his Ph.D. degree in Plant Biology and Ecology (1998) at the Université de Paris XI, France. In 2004, he obtained accreditation to direct research (HDR) at the Université de Paris VII. During his research career, he has worked on various projects related to biochemistry, analytical chemistry and systems biology (proteomics, transcriptomics and metabolomics) utilising model organisms such as humans, animals, plants, fungi and microorganisms.  

After graduation, he was employed at the French institute INRA (Institut National de la Recherche Agronomique). He participated in industrial projects to develop lactose fermenting bacteria. At the same institute, he worked for four years on projects pertaining to the remodulation of plant polysaccharides in order to engineer a satisfactorily digestible product which is important for animal feeding and bioproducts. The previously described projects relied on collaborations with industrial partners.  

After relocating to Canada, he initially worked as a professional research associate at the University of Saskatchewan. His project focused on developing a new generation of antifungal and antimicrobial agents for crop protection. At the University of Regina, he worked as a Facility Manager responsible for operating and maintaining the high-throughput proteomics platforms in the Proteomics and Genomics core facility. His key responsibilities included preparing and processing samples and developing methods for large-scale proteomic projects using the state-of-the-art Orbitrap Elite mass spectrometer coupled to EASY nLC 1000. Since 2017, he has been working as a Biological Mass Spectrometrist at the University of Ottawa’s John L. Holmes Mass Spectrometry Facility. His main responsibilities include the preparation and processing of biological samples and the development of large-scale proteomics and metabolomics analysis methods using state-of-the-art mass spectrometers: Orbitrap Fusion, Q-Exactive and Waters SYNAPT G2HDMS. His duties also include providing scientific consultation, designing sample preparation protocols and assisting in the development and implementation of experimental mass spectrometry-based methods. He has led and supervised technical training courses and workshops on mass spectrometry for researchers, graduate and non-graduate students. In the last four years, he has organized workshops and taught the graduate course CHM 8352. 

During his research and managerial career, Zoran has acquired a strong background in proteomics, metabolomics, liquid chromatography, mass spectrometry, and bio-molecular purification, characterization, quantification and identification techniques. His work in the research facility at the University of Saskatchewan, Regina, and Ottawa encompassed maintenance, calibration and troubleshooting of sophisticated analytical instrumentation such as different types of Liquid Chromatography (HPLC, UPLC or nLC and FPLC) and High Resolution Mass Spectrometers (HRMS). 

He has contributed to grant writing and actively pursues research partnership opportunities by collaborating with industry and academia. His facility provides services for different users in Canada, USA, Germany, Spain, Italy, Japan, Mexico, Brazil, China, Serbia and Russia. He is the author/co-author of more than 70 academic journal articles, book chapters and patents. 

Nico Huttmann

Nico Hüttmann

Data Analyst

Nico Hüttmann is part of the JLHMS facility as a Data Analyst since 2022. He obtained his B.Sc. in Biomolecular Engineering from the Technical University of Darmstadt, Germany, and his M.Sc. degree in Chemistry from the University of Ottawa. He conducted his research under Dr. Maxim Berezovski investigating the surface proteome of extracellular vesicles from breast cancer cell lines by mass spectrometry.  

During his time in Canada, he worked on several collaborative projects applying MS-based proteomics to answer diverse biological questions in the fields of aptamers, biomarker discovery, cancer biology, food science, immunology and iron metabolism. He has been part of the Proteomics Workshop and served on the organizing committee of the 2022 Metabolomics Workshop of the JLHMS facility.  Besides proteomics, Nico has experience with affinity-mass spectrometry to determine and characterize protein-antibody and -aptamer binding epitopes. 

Nico’s duties within the JLHMSF include data handling, developing new analysis methods and pipelines, consulting project design and analysis, and providing and teaching data analysis of proteomics and metabolomics data. Most data analysis for the JLHMSF is conducted within the R statistical programming environment with the in-house pOmics R package. It contains curated functions for statistical, bioinformatics and machine learning-based analysis and visualization of qualitative, quantitative and PTM proteomics data. Using R as the programming language allows clients of the facility to understand, replicate and share their analysis code with collaborators and journals. Outside the lab, Nico is a passionate tennis and handball player. 

Contact Us

Biological facility

Zoran Minic
[email protected]
Marion Hall - Room 02
Ottawa, ON K1N 1A2
Tel: 613-562-5800 ext. 1626