Our Projects

Within the last decade, extracellular vesicles (EVs) have been recognized as a novel mechanism of intra- and intercellular communication via the delivery of bioactive molecules that mainly comprise proteins, metabolites, lipids, and nucleic acids, including messenger RNAs (mRNAs) and microRNAs (miRNAs). EVs are also found in biological fluids such as blood, saliva, cerebrospinal fluid, and urine. Furthermore, they are implicated in various pathogeneses and could contain biomarkers associated with specific human diseases. Moreover, profiling the contents of EVs may further elucidate their role in disease progression and treatment, as well as enable the identification of therapeutic targets. In recent years, it has been proposed that EVs could be utilized in the development of novel therapies. However, in order to employ EVs for the diagnosis and treatment of human diseases, appropriate methods for their isolation must be developed, and their molecular composition, functionality, and the distribution of EV cargo must be investigated. Our facility is particularly focused on the study of extracellular vesicles for diagnosis and treatment of various human diseases.

https://www.mdpi.com/journal/biomedicines/special_issues/84Y13EZ22P