Explore our principal investigators!

Principal investigators

Tommy Alain

Tommy Alain

mRNA translation, viral immunotherapies, cancer biology

Steffany Bennet

Steffany Bennet

Lipidomics, bioinformatics, neurobiology

Jason Berman

Jason Berman

Genetic and xenotransplantation models of cancers and rare diseases

Shawn Beug

Shawn Beug

Cancer Biology, Immunotherapy, Cell Death, Inflammation

Alexandre Blais

Alexandre Blais

Muscle development, transcription, and chromatin regulation

Kin Chan

Kin Chan

Cancer biology, model systems, mutation signatures

David Cook

David Cook

Cancer biology, cellular plasticity, single-cell genomics

Willard Costain

Willard (Will) Costain

Associate member (Pharmacology, Health, Biotherapeutics, Bioassay, Genomics)

Marceline Côté

Marceline Côté

Viral signaling, intracellular trafficking

Jean-François Couture

Jean-François Couture

Structural biology, X-ray crystallography, chromatin regulation

logo uOttawa

Miroslava Cuperlovic-Culf

Associate member (Computational biology, bioinformatics, metabolomics, systems biology, applied data mining, machine learning, NMR spectroscopy)

Damien D'Amours

Damien D'Amours

Chromosome structure, regulation of cell division, DNA repair, chromatin remodeling, cancer biology, model systems

Michael Downey

Michael Downey

Protein lysine acetylation and polyphosphate biology

Daniel Figeys

Daniel Figeys

Proteomics, microbiome analysis

Morgan Fullerton

Morgan Fullerton

Metabolic kinases, nutrient sensing, immunometabolism, cardiometabolic diseases

Suresh Gadde

Suresh Gadde

Translational nanomedicine, biomaterials

Francesco Gentile

Francesco Gentile

Computational drug discovery, deep learning

Derrick Gibbings

Derrick Gibbings

Micro RNAs, autophagy, neurodegenerative disorders

Ashkan Golshani

Ashkan Golshani

Peptite design, AI-driven drug development and protein engineering

Mary-Ellen Harper

Mary-Ellen Harper

Mitochondrial bioenergetics and uncoupling, glutathione redox, diabetes, obesity, cardiomyopathies

Jennifer Hill

Jennifer Hill

Associate member (Proteomics, cell surface proteins, biotherapeutic characterization and development)

Arezu Jahani-Asl

Arezu Jahani-Asl

Glioblastoma, Intellectual Disability, Stem Cells

Anna Jezierski

Anna Jezierski

Associate member (Stem cell differentiation, blood brain barrier, 3D bioprinting, engineered cell-based therapies, rare diseases)

Mads Kaern

Mads Kaern

Synthetic biology, gene network analysis

Mireille Khacho

Mireille Khacho

Mitochondrial dynamics, stem cell biology, tissue regeneration

Mathieu Lavallée-Adam

Mathieu Lavallée-Adam

Proteomics, network analysis, machine learning, bioinformatics

Seung-Hwan Lee

Seung-Hwan Lee

Immunotherapy, immunometabolism, natural killer cells, radiobiology

Scott McComb

Scott McComb

Associate member (Cancer immunotherapy discovery, high-throughput functional immune assays, CAR-T therapies, multi-specific antibodies)

Lynn Megeney

Lynn Megeney

Cell fate control, stem cell biology

Keir Menzies

Keir Menzies

NAD+ signaling and energy metabolism, mitochondria, neuromuscular diseases

Arvind Mer

Arvind Mer

AI, machine learning, bioinformatics, computational biology, cancer

Erin Mulvihill

Erin Mulvihill

Lipid metabolism, intestinal biology, diabetes, cardiovascular biology, mouse genetics

Mona Nemer

Mona Nemer

Molecular cardiology, transcriptional regulation, cardiac birth defects

Matthew Pamenter

Matthew Pamenter

Natural adaptations to hypoxia, comparative physiology, neurobiology, mitochondrial function

Izabella Pena

Izabella Pena

Metabolic and mitochondrial function in epilepsies and neurodegeneration, zebrafish models

Theodore Perkins

Theodore Perkins

Bioinformatics, image analysis, gene regulation

Maxime W. Rousseaux

Maxime W. Rousseaux

Neurodegeneration, Parkinson's disease, genome engineering, mouse models

Adam Rudner

Adam Rudner

Phage biology, yeast genetics, chromosome biology

Michael Rudnicki

Michael Rudnicki

Stem cells, myogenesis and muscle regeneration, muscular dystrophy, neuromuscular disease

Ryan Russell

Ryan Russell

Autophagy, cancer biology, Crohn's disease

Jagdeep Sandhu

Jagdeep Sandhu

Associate member (Parkinson’s disease, neuroinflammation, innate immunity, NLRP3 inflammasome, extracellular vesicles, therapeutics)

Julie St-Pierre

Julie St-Pierre

Metabolomics, mitochondria, metabolic adaptations in cancer and chemotherapies

Xiaojian Shao

Xiaojian Shao

Associate member (Bioinformatics, machine learning and deep learning, DNA methylation, single cell genomics)

William Stanford

William Stanford

Stem cells, cancer biology, epigenetic control of cell fate, regenerative medicine

Alain Stintzi

Alain Stintzi

Inflammatory bowel diseases, microbiome analysis, transcriptional regulation

Albert Stolow

Albert Stolow

Molecular photonics

Laura Trinkle-Mulcahy

Laura Trinkle-Mulcahy

Proteomics, phosphatase regulation, cell signaling, microscopy

Barbara Vanderhyden

Barbara Vanderhyden

Ovarian cancer, tumour microenvironment, chromatin remodeling, therapeutics

Lisheng Wang

Lisheng Wang

Embryonic stem cells, cancer stem cells, cell signaling

Xuhua Xia

Xuhua Xia

Evolutionary molecular genetics, bioinformatics, molecular phylogenetics